About this trial
Surgical extraction of impacted third molar is the most common surgical procedure performed in oral and maxillofacial surgery. The immediate post operative complications after 3rd molar surgery are pain, swelling and trismus while delayed post operative complications are mostly seen on the distal surface of second molar due to distal bone loss which include prolonged sensitivity due to increased periodontal pocket depth, gingival recession and root exposure.
When PRF clot is given in wound, it causes alterations of the cellular ratios in the wound blood clot, leading to replacement of blood cells with Platelets and growth factors stimulating all phases of healing which will improve the immidiate and delayed post operative complications The purpose of present study is to compare the clinical outcomes in the treatment of senstivity and periodontal pockets at the distal aspect of second molar following surgical extraction of impacted third molar using PRF or Blood clot alone.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Impacted third molar (as per Operational Definition) with fully erupted second molars bilaterally.
Impacted Third molar with Class 2 and Level B according to Pell and Gregory's classification (Annexure B) with mesioangular or horizontal angulation of impaction
Periodontal pocket depth > 4mm and Clinical attachment loss > 1mm at distal side of second molar
Age 18-40 years, both genders.
Disqualifiers
Any Systemic Disease i.e. Uncontrolled Diabetes mellitus, Uncontrolled hypertension, Ischemic heart disease, bleeding disorders, Autoimmune diseases or immunocompromised patients
Decayed or recommended for extraction second molars on either side.
Allergic to Amoxicillin to standardize Antibiotic therapy protocol.
Untreated periodontal condition.
Trial design
Parallel
Treatments tested in this trial
Platelet rich fibrin
Other interventionAfter surgical extraction of impacted mandibular 3rd molar PRF will be placed in extraction socket
Treatment groups
Trial outcomes
Primary outcomes
Periodontal Pocket Depth
Periodontal pocket depth will be measured as a distance between gingival margin and base of the periodontal pocket in millimeters by Williams periodontal probe .
Senstivity
Response of patient elicited by painful stimulus i.e Tactile stimulus which is characteristically of short duration will be measured by Tactile method i.e. scratching the distal surface of second molar at cemento-enamel junction with dental explorer on Numeric scale with values from 0 to 10, 0 being the least/no sensitivity and 10 being the worst
Clinical attachment loss
Clinical attachment loss will be measured as a distance between cemento-enamel junction of second molar to the base of periodontal pocket in millimeters by williams periodontal probe
Sponsors and contacts
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