The Effect of Prolonged Sugar-Free Chewing Gum Mastication on Self-Reported Fatigue Levels and Changes of Static and Dynamic Surface Electromyography Parameters in Young Individuals With and Without Temporomandibular Joint Disorders.

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age19-35
SponsorUniversity of Milan

About this trial

This case-control study investigates fatigue induced by prolonged gum mastication in individuals with temporomandibular disorders (TMD). The study addresses two primary questions:

How does self-reported fatigue, measured with a visual analogue scale (VAS), change during sustained chewing? How do static and dynamic surface electromyographic (sEMG) parameters evolve over the same period? Participants with TMD will be compared with healthy controls to determine group differences in perceived fatigue and EMG responses.

All participants will undergo baseline EMG assessment, then chew sugar-free gum continuously for 3 minutes, alternating sides without rest. After each 3-minute interval, static and dynamic EMG recordings will be obtained and participants will rate their fatigue on the VAS. This cycle may be repeated up to six times (maximum 18 minutes). Participants are free to stop chewing at any time if fatigue becomes intolerable.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age 19-35 years

Chewing-gum users, even occasional

Good general health

Good oral health

Disqualifiers

Non chewing gum users

History of neurological disorders

History of musculoskeletal diseases

History of facial or cervical injuries

Trial population

The study population will consist of volunteer participants recruited from the undergraduate dentistry program and postgraduate specialty training programs at the University of Milan.

Trial design

Design model

Case-control

Time perspective

Cross-sectional

Treatments tested in this trial

  • Mastication of sugar-free chewing gum

    Other intervention

    The chewing task will last for a maximum of 18 minutes.

Treatment groups

30 Participants
are divided into 2 treatment groups
Group A: Case group (subjects with TMD)1 intervention
Group B: Control group (TMD-free subjects)1 intervention

Trial outcomes

Primary outcomes

1

Self-reported (subjective) fatigue after prolonged sugar-free chewing gum mastication

Time frame
The whole session has a maximum duration of 18 minutes, assessments are done every 3 minutes

Secondary outcomes

1

Changes of static and dynamic surface electromyography (sEMG) parameters after prolonged mastication of sugar-free chewing gum

Time frame
The whole session has a maximum duration of 18 minutes, assessments are done every 3 minutes

Other outcomes

Sponsors and contacts

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