About this trial
The aim of this study is to evaluate the effects of the steep Trendelenburg position in robotic prostatectomy cases, where anesthesia depth is monitored using BIS and cerebral perfusion is tracked with NIRS, and to determine the incidence of neurocognitive dysfunction using the MoCA test in the postoperative period.
Steep Trendelenburg position and CO₂ pneumoperitoneum during robotic radical prostatectomy lead to significant changes in intracranial pressure and cerebral oxygenation, which may contribute to postoperative neurocognitive dysfunction (POCD). Monitoring anesthesia depth with Bispectral Index (BIS) and cerebral perfusion with Near-Infrared Spectroscopy (NIRS) may help detect early neurocognitive changes, and MoCA test assessments will reveal a measurable decline in cognitive function postoperatively.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Age ≥ 65 years
ASA II-III risk score
Patients scheduled for robotic radical prostatectomy
Patients who voluntarily agree to participate
Disqualifiers
Age < 65 years
History of neurological or psychiatric disorders
Inability to undergo robotic surgery
Conversion to open prostatectomy during surgery
Trial population
Patients aged 65 years and older with ASA II-III risk scores, undergoing robotic radical prostatectomy
Trial design
Cohort
Prospective
Treatments tested in this trial
Montreal Cognitive Assessment
Diagnostic testPreoperative and postoperative MoCA test scores
Treatment groups
Trial outcomes
Primary outcomes
MoCA
Preoperative MoCA test scores
MoCA
postoperative MoCA test scores
Secondary outcomes
NIRS
NIRS values (right \& left)
Sponsors and contacts
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This trial is not recruiting at the moment. You can still explore other options: