The Effect of Steep Trendelenburg Position on Neurocognitive Functions in Robotic Radical Prostatectomy Cases

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexMale
Age65-100
SponsorAnkara City Hospital Bilkent

About this trial

The aim of this study is to evaluate the effects of the steep Trendelenburg position in robotic prostatectomy cases, where anesthesia depth is monitored using BIS and cerebral perfusion is tracked with NIRS, and to determine the incidence of neurocognitive dysfunction using the MoCA test in the postoperative period.

Steep Trendelenburg position and CO₂ pneumoperitoneum during robotic radical prostatectomy lead to significant changes in intracranial pressure and cerebral oxygenation, which may contribute to postoperative neurocognitive dysfunction (POCD). Monitoring anesthesia depth with Bispectral Index (BIS) and cerebral perfusion with Near-Infrared Spectroscopy (NIRS) may help detect early neurocognitive changes, and MoCA test assessments will reveal a measurable decline in cognitive function postoperatively.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age ≥ 65 years

ASA II-III risk score

Patients scheduled for robotic radical prostatectomy

Patients who voluntarily agree to participate

Disqualifiers

Age < 65 years

History of neurological or psychiatric disorders

Inability to undergo robotic surgery

Conversion to open prostatectomy during surgery

Trial population

Patients aged 65 years and older with ASA II-III risk scores, undergoing robotic radical prostatectomy

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Montreal Cognitive Assessment

    Diagnostic test

    Preoperative and postoperative MoCA test scores

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

MoCA

Preoperative MoCA test scores

Time frame
preoperatively
2

MoCA

postoperative MoCA test scores

Time frame
day 1

Secondary outcomes

1

NIRS

NIRS values (right \& left)

Time frame
intraoperatively

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

This trial is not recruiting at the moment. You can still explore other options: