The Effect of Supplementation With Fish Oil (EPAX EVOLVE 05) on Sperm Quality
ConditionInfertility, Male
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age18-55
SponsorEpax Norway AS
About this trial
The study will enrol men that have a poor sperm quality. They will take either a placebo or fish oil capsule (2 per day) for 3 months. At the beginning and end of the study the participant will be asked for a sperm sample for measuring quality parameters.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Men aged 18-55
Referred for or claiming a semen analysis.
Willing to have at least 2 days abstinence of sexual activity prior to a sperm sample being taken.
Willing to refrain from omega-3/cod liver oil supplementation during the study. Use of other supplements is allowed.
Disqualifiers
Known allergy to fish products
Historically, known, or suspected bacterial infection in reproductive organs
Varicocele suspected from physical examination
Azoospermia
Trial design
Design model
Single group
Treatments tested in this trial
Very Long Chain Polyunsaturated Fatty Acids
Dietary supplementFish oil with DHA and VLCPUFA
Comparator arm (DHA)
Dietary supplementOil containing equal DHA content to active arm
Treatment groups
80 Participants
are divided into 2 treatment groupsGroup A: PlaceboActive comparator 1 intervention
Group B: VLC-PUFAExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Total Progressive Motile count will be measured pre- and post-intervention and compared to the comparator arm.
The motile count will be performed by competent operators at each clinical site.
Time frame
From baseline to end of intervention at 3 monthsSponsors and contacts
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Source ClinicalTrials.gov