"The Effect of The Combination Therapy of Statin and SGLT2i in The Treatment of Ischemic Heart Disease"

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age50-80
SponsorFayoum University

About this trial

correlate the serum level of statin and SGLT2i when given as polytherapy with HPLC in ischemic heart failure patients and their laboratory tests (cholesterol, LDL, HDL and TG...)

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

we include patients established ischemic heart failure seen by a primary care provider to diagnose ischemic heart disease,

They assessed the use of statin with SGLT2i.

Disqualifiers

We exclude patients with

liver dysfunction.

renal dysfunction.

fungal infection.

Trial population

the health care provider asks about patient's symptoms which may experience: * Chest pain, especially after physical exertion * Dizziness or fainting * Heart palpitations, which may feel like your heart fluttering or skipping beats * Shortness of breath * Swelling in your feet or ankles * brain natriuretic peptide (BNP) with 70% sensitivity and 99% specificity and N-terminal proBNP (NT-proBNP) with 99% sensitivity and 85% specificity which are Other HF-specific laboratory tests (especially in patients with a high possibility of heart failure) included. (18) * chest X-ray, transthoracic echocardiography (TTE), computerized tomography (CT) scans and magnetic resonance imaging (MRI) also other diagnostic tests for HF. (19)

Trial design

Design model

Case-only

Time perspective

Other

Treatments tested in this trial

  • Statin and SGLT2i

    Drug

    Statin as atrovastatin SGLT2i as dapagliflozin

Treatment groups

90 Participants
are divided into 3 treatment groups
Group A: Patients has ischemic heart failure1 intervention
Group B: Patients has ischemic heart1 intervention
Group C: Patients has heart disease1 intervention

Trial outcomes

Primary outcomes

1

The Effect of The combination Therapy of Statin and SGLT2i in The Treatment of Ischemic Heart disease

correlate the serum level of statin and SGLT2i when given as polytherapy with ECG in ischemic heart failure patients and their laboratory tests (cholesterol, LDL, HDL and TG...)

Time frame
Three months of follow up

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.