The Effectiveness and Safety of Combined Research on Uremic Sarcopenia
ConditionSarcopenia
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorNingbo Medical Center Lihuili Hospital
About this trial
Objective: To investigate the clinical efficacy and safety of mindfulness meditation during dialysis combined with pre-dialysis progressive resistance training (PRT) for sarcopenia in patients undergoing maintenance hemodialysis (MHD).
Methods: In the randomized controlled trial, 76 MHD patients with sarcopenia were divided into three groups: control group (CG), sports group (SG), and intervention group (IG). All groups received standard dialysis, health education, and dietary guidance. The SG received pre-dialysis PRT, while the IG added mindfulness meditation during dialysis. Efficacy and safety were evaluated at baseline and after 12 weeks. Ultrasound assessments of muscle mass were conducted at baseline, week 4, week 8, and week 12.
Eligibility criteria
Qualifiers
Meet the updated Asian diagnostic criteria for sarcopenia
Stable vital signs and general physical condition
Willing and able to cooperate with supervised exercise training
Regular hemodialysis 3 times per week for at least 3 months
Disqualifiers
Acute cardiovascular or cerebrovascular events within the previous 3 months
Cognitive dysfunction affecting study cooperation and exercise completion
Severe osteoarticular or limb movement disorders preventing standardized exercise training
Active systemic infection
Trial design
Treatments tested in this trial
- Received mindfulness meditation training during dialysis in addition to exercise therapy.
Treatment groups
76 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov