The purpose of this study is to learn how aging affects muscle endurance during resistance exercise, and how oxygen delivery to the muscles plays a role in these changes. To answer this question, we are comparing how many repetitions of a leg exercise (knee extensions) younger and older adults can do at different exercise intensities. We will also look at how the muscles use oxygen during these exercises.
Participants will take part in 12 different exercise sessions. In each session, they will perform as many knee extensions as possible using different amounts of weight-consisting of 20%, 30%, 40%, 50%, 60% and 70% of the maximum weight they can lift one time. Each weight will be tested both with and without a cuff on the leg that temporarily reduces blood flow to the muscle.
Able to understand and communicate in English
19-35 years of age
65 years of age or older
All "No" answers on the CSEP Get Active questionnaire or doctors' approval to participate
BMI lower than 18 or greater than 32
Current use of cigarettes or other nicotine devices
Any major uncontrolled cardiovascular, muscular, metabolic, and/or neurological disorders
Any medical condition impacting the ability to participate in maximal exercise
Single group
Knee extension exercise
Other interventionMaximum repetitions of knee extension exercise at 20%, 30%, 40%, 50%, 60% and 70% of participants one rep max with and without blood flow occlusion
Maximum repetitions performed during knee extension exercise
The primary outcome of the study will be the maximum number of knee extension repetitions that participants are able to perform at varying resistive exercise loads.
Local muscle tissue oxygenation during knee extension exercise
Muscle tissue oxygenation status will be assessed during each knee extension exercise intervention using oxygen sensors placed on the outside of the thigh.
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