Health TrialsbyHealthPanel

The Effects of Brief Periods of Exercise on Blood Pressure

ConditionsHypertension (HTN)Pre Hypertension
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-55
SponsorUniversity of Hartford

About this trial

High blood pressure is a common medical condition that affects the body's arteries. It's also called hypertension. Untreated hypertension increases the risk of heart attack, stroke and other serious health problems. Exercise is a promising tool in hypertension management. Regular participation in exercise improves vascular health, heart and lung function, and multisystem health. However, the direct evidence of the treatment effects of a brief period of exercise on blood pressure in individuals with hypertension is limited. A brief period of exercise refers to an exercise protocol that only lasts for a very short period of time, such as 5-10 minutes.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

18-55 yrs.

24 hour average BP >110/70 mmHg, but < 160 systolic blood pressure

Able to provide informed consent

Disqualifiers

Currently taking anti-hypertensive medication smokers and alcohol drinkers Inability to undertake exercise intervention (resistance and isometric exercise)

Trial design

Design model

Parallel

Treatments tested in this trial

  • wall-squat

    Behavioral

    the experimental group will complete the four sets of wall-squats at four different times across the day: morning, noon, afternoon, night.

  • wall-squat-tradition

    Behavioral

    The other exercise group will do 4 sets of wall squat in a continuous way.

Treatment groups

45 Participants
are divided into 3 treatment groups
Group A: Non-Ex control groupNo intervention 0 interventions
Group B: Clustered Ex ConditionActive comparator 1 intervention
Group C: Scattered Ex ConditionExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

24 h blood pressure

The average, peak and variations of 24 h SBP and DBP, daytime SBP and DBP, night time SBP and DBP will be measured before and after the intervention.

Time frame
From the enrollment to the end of the study at six weeks

Secondary outcomes

1

endothelial function

endothelial function measured by flow mediated dilation

Time frame
at baseline (Day 1) and Week 6
2

arterial stiffness

arterial stiffness measured by pulse wave velocity

Time frame
at baseline (Day 1) and week 6

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Hartford

Lead sponsor

Source ClinicalTrials.gov
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