This study was a single-center RCT study to compare the effect of preoperative prehabilitation treatment of ileostomy contents filtrate reinfusion through distal ileocolon or retention of enema colon with that of traditional treatment in patients with bowel function after stoma closure.
aged 18-85 years old
Karnofsky performance status (KPS)≥70%; Or ECOG score 2 points or less
rectal cancer confirmed by preoperative pathology
in the rectum resection before low, low colorectal anastomosis or after neoadjuvant therapy of patients
cannot complete treatment
the history of the anorectal surgery
preoperative bowel dysfunction such as diarrhea, irritable bowel syndrome and functional constipation, etc.)
postoperative anastomotic fistula and stricture
Parallel
preoperative prehabilitation treatment of ileostomy contents filtrate reinfusion through distal ileocolon or retention of enema colon
BehavioralThe contents of the ileostomy were collected and placed in a wide mouth container, mixed with 500mL normal temperature saline, and placed in a funnel with double layer medical gauze. The filtrate of the ileal contents was collected and placed into an enema for use. The catheter was placed into the ileal output end of the ostomy through anterograde enema or transanal retention enema, and slowly infused for 15-20 minutes, 2-3 times a day for 4 weeks. The adverse reactions such as abdominal pain, abdominal distension and fever were observed. The number, time, antegrade/retrograde prehabilitation operation, adverse reactions during the operation and other special conditions were recorded every day, and the weight of the patient was recorded
The extent of low anterior resection syndrome
low anterior resection syndrome score（0-42，Higher scores indicate more severe symptoms）
the intestinal function recovery
The first postoperative exhaust and defecation time
Concentration of C-reactive protein
Concentration of C-reactive protein after surgery
Quality of Life Questionnaire Core 30
Quality of Life Questionnaire Core 30（0-100，standardscore，A higher score in the symptom domain indicates a worse quality of life）
fecal incontinence
The Cleveland clinic fecal incontinence score（0-20，Higher scores indicate more severe symptoms）
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