The Effects of Exercise Snacks on Endothelial Function and Body Composition in Overweight Individuals
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-35
SponsorWeifang Medical University
About this trial
This randomized controlled trial investigates the effects of two types of stair-climbing exercise snacks versus moderate-intensity continuous training on vascular health, body composition, and blood lipids in overweight or obese adults. Participants will be assigned to one of four groups for 6-8 weeks. The control group receives no exercise intervention. Primary outcomes include endothelial function (ultrasound), body composition (InBody), and lipid profile (blood test).
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age: 18-35 years old (male, female);
Clear consciousness, stable vital signs;
Able to understand and follow simple instructions;
No regular exercise for at least 3 months;
Disqualifiers
There are other serious diseases, such as tumors;
There are other neurological diseases;
There are serious diseases that simultaneously affect the heart, liver, kidneys, endocrine system or hematopoietic system;
There is a history of alcohol or drug abuse;
Trial design
Design model
Parallel
Treatments tested in this trial
Short-term stair climbing exercise snack group
BehavioralAdopt a fragmented approach, climbing stairs 4-5 times a day, each time climbing 5 floors (approximately 1 minute per session), with at least 1 hour of interval between each session, and spread throughout the daily activity periods. Exercise 3-5 days per week for a total of 6-8 weeks.
Long-duration stair climbing exercise snack group
BehavioralOn the basis of climbing stairs 4 to 5 times a day, increase the single exercise volume: complete 2 or 3 sets of climbing 5 floors of stairs each time (that is, the total number of floors climbed each time is 10 or 15), with no more than 1 minute of rest between sets. The intervals between each exercise should be at least 1 hour. Exercise 3 to 5 days a week, for a total of 6 to 8 weeks of intervention.
Moderate-intensity continuous exercise（MICT）
BehavioralExercise 3 to 5 days per week for a total of 6 to 8 weeks. Perform 30 minutes of moderate-intensity running training every day.
Treatment groups
60 Participants
are divided into 4 treatment groupsGroup A: Short-term stair climbing exercise snack groupExperimental treatment 1 intervention
Group B: Long-duration stair climbing exercise snack groupExperimental treatment 1 intervention
Group C: Moderate-intensity continuous exerciseExperimental treatment 1 intervention
Group D: control groupNo intervention 0 interventions
Trial outcomes
Primary outcomes
1
Flow-mediated dilation (FMD, relative percentage)
Flow-mediated dilation expressed as a percentage of the baseline brachial artery diameter.Unit of Measure: %
Time frame
Measured at baseline, mid-intervention (approximately 3-4 weeks), and post-intervention (after 6-8 weeks).2
Body fat mass
Body fat mass measured by bioelectrical impedance analysis (InBody device). Unit of Measure: kg
Time frame
Measured at baseline, mid-intervention (approximately 3-4 weeks), and post-intervention (after 6-8 weeks).3
Time to peak dilation
Time required to reach maximal dilation after cuff deflation.Unit of Measure: seconds
Time frame
Measured at baseline, mid-intervention (approximately 3-4 weeks), and post-intervention (after 6-8 weeks).4
Basal brachial artery diameter
Baseline diameter of the brachial artery before cuff inflation.Unit of Measure: mm
Time frame
Measured at baseline, mid-intervention (approximately 3-4 weeks), and post-intervention (after 6-8 weeks).Secondary outcomes
1
Systolic blood pressure (SBP)
Systolic blood pressure measured using an electronic sphygmomanometer.Unit of Measure: mmHg
Time frame
Measured at baseline, mid-intervention (approximately 3-4 weeks), and post-intervention (after 6-8 weeks).2
Serum high-density lipoprotein (HDL) cholesterol concentration
Fasting serum HDL cholesterol concentration measured from blood samples. Unit of Measure: mmol/L
Time frame
Measured at baseline and post-intervention (after 6-8 weeks).3
Diastolic blood pressure (DBP)
Diastolic blood pressure measured using an electronic sphygmomanometer. Unit of Measure: mmHg
Time frame
Measured at baseline, mid-intervention (approximately 3-4 weeks), and post-intervention (after 6-8 weeks).4
Heart rate
Heart rate measured using an electronic sphygmomanometer.Unit of Measure: bpm (beats per minute)
Time frame
Measured at baseline, mid-intervention (approximately 3-4 weeks), and post-intervention (after 6-8 weeks).Locations
Sponsors and contacts
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Source ClinicalTrials.gov
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