The Effects of Moderate Intensity Cycle Ergometer vs. Treadmill Training on Physiological Resilience in Older Adults

ConditionOlder People
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age60-80
SponsorUniversity of Nottingham

About this trial

Government guidelines suggest that we should all take part in approximately two and a half hours each week of moderate-intensity aerobic exercise. Older adults are particularly important as their overall health may decline as they get older. Therefore, exercising is important especially for older adults to improve heart and muscle health and functioning in carrying out tasks of daily living. The overall effects of aging on the body can make people less likely to withstand challenges to the body - this is termed 'resilience'. Although aerobic exercise is not super easy and requires continuity, it is not extremely difficult to get used to. However, we still do not know if some types of aerobic exercise are better for you than others at improving resilience. Therefore, this study will look at cycling vs walking to see if one is better at improving resilience in older adults who are 60-80 years old. You will be trained on either a treadmill or cycle ergometer and these exercise sessions will be done over 5 weeks, 3 days a week. Each session will last 40 minutes, start with warm-up and end with cool-down sessions. Assessments will include heart, lung, muscle, and memory and thinking measurements, all of which will be taken before and after the intervention period. This work will help us to better understand how we can improve exercise prescriptions for older adults to sustain their health and functioning in their daily life.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Participant is willing and able to give informed consent for participation in the study

Participants who are able to perform exercises safely and freely

Participants who are 60-80 years old

Disqualifiers

Cardiopulmonary diseases except for well-controlled hypertension and asthma

Severe cognitive impairment

Joint disorders avoiding exercise participation

A recent heart attack, unstable angina, or severe heart failure

Trial design

Design model

Parallel

Treatments tested in this trial

  • treadmill exercise

    Other intervention

    Intervention consists of exercises only. Participants in this group will walk on a treadmill. The heart rates of the participants will be monitored with a heart rate monitor while exercising in order to maintain moderate-intensity.

  • cycle ergometer exercise

    Other intervention

    Intervention consists of exercises only. Participants in this group will cycle on an ergometer. The heart rates of the participants will be monitored with a heart rate monitor while exercising in order to maintain moderate-intensity.

Treatment groups

36 Participants
are divided into 3 treatment groups
Group A: treadmill exerciseExperimental treatment 1 intervention
Group B: cycle ergometer exerciseExperimental treatment 1 intervention
Group C: control groupNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

The change in vastus lateralis mass

Bioelectrical impedance analysis (BIA) and ultrasound will be used for this. Muscle thickness, fascicle length, and pennation angle will be measured on ultrasound. BIA is simple to use, places a minimal burden on individuals, uses lightweight and inexpensive equipment, and, most significantly, provides no radiation risk compared to many other methods. It is also found feasible and reliable for the measurement of muscle mass for adults in clinical settings. Ultrasonography is also a technology that is portable, safe, and clearly distinguishes between muscle and subcutaneous fat tissues as well as a valid and novel tool for muscle mass assessment.

Time frame
at baseline (pre-intervention) and at the week 5 (post-intervention)
2

The changes of muscle strength with maximum voluntary contraction of knee extension

Maximum voluntary contraction is a standardized technique for assessing muscle strength in healthy older adults. Knee extension strength will be measured with an isometric dynamometer.

Time frame
at baseline (pre-intervention) and at the week 5 (post-intervention)
3

The change in cardiorespiratory fitness (CRF) capacity via the Ekblom-bak (EB) test

The EB-test consists of exercise at one standardized, low work rate followed by a higher, individually set work rate. Both work rates are performed for 4 minutes at a cadence of 60rpm on a cycle ergometer. The individual higher work rate is chosen by the researcher according to the participants' gender, age, and training background. The higher work rate aims to reach the Borg rate of perceived exertion (RPE) 12-16. Heart rate is measured during the last minute of each work rate (at 3:15, 3:30, 3:45, and 4:00). Then, VO2max is estimated with a formula.

Time frame
at baseline (pre-intervention) and at the week 5 (post-intervention)
4

The difference in neuromuscular function via force accuracy task

Force accuracy is an important parameter since most daily activities are conducted at submaximal levels, where force fluctuation can be observed and reduce the ability to create an intended movement. Force accuracy will be measured on OTBiolab+ application.

Time frame
at baseline (pre-intervention) and at the week 5 (post-intervention)

Secondary outcomes

Other outcomes

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