Health TrialsbyHealthPanel

The Effects of Night Shift Work on Health Across the Menstrual Cycle

ConditionsSleep DeprivationMenstrual CycleBrain HealthMetabolismMicrobiotaImmune System
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-35
SponsorUppsala University

About this trial

The study aims to investigate the effects of sleep deprivation on women's health across different phases of the menstrual cycle.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

Use of hormonal contraceptives

Chronic disease

Regular use of nicotine

Use of medication

Trial design

Design model

Single group

Treatments tested in this trial

  • Investigate sleep deprivation

    Other intervention

    Sleep deprivation Devices used: Dreem band for EEG Actiheart Tobii Eye tracker Blood glucose monitor Blood pressure cuff Mira fertility tracker Galvanic skin response K5: wearable metabolic system Fitbit: wearable technology Withings sleep analyzer Body composition monitor

Treatment groups

60 Participants
are divided into 1 treatment group
Group A: Sleep deprivationExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

The effect of sleep deprivation vs sleep on brain health across the menstrual cycle

Blood analysis for neurodegenerative biomarkers, specifically Tau protein phosphorylated at amino acid 181 and 231, Aβ40 and Aβ42, GFAP, NfL.

Time frame
1 year
2

The effects of sleep deprivation across the menstrual cycle on EEG

The Dreem headband will be used to record EEG, assessing wakefulness levels during the sleep deprivation night through spectral power analysis. It will also be used to generate a hypnogram for sleep stage classification.

Time frame
1 year
3

The effects of sleep deprivation on metabolic function (TEE)

Energy Expenditure is measured with the K5 wearable system to monitor VO₂ and VCO₂ in real-time, assessing total energy expenditure (TEE).

Time frame
2 years
4

The effects of sleep deprivation on glucose metabolism

Assessed with an Oral Glucose Tolerance Test (OGTT) and continuous blood glucose monitoring.

Time frame
1 year

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Uppsala University

Lead sponsor

Source ClinicalTrials.gov
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