The Effects of One Day of Activity on the Next Day's Exercise Response
ConditionInactivity, Physical
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-30
SponsorConcordia University Wisconsin
About this trial
Exercise can reduce the risk of several chronic diseases. However, recent studies have suggested sitting for too long before exercising can decrease exercise benefits. This study will help determine why this may occur.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
• between the ages of 18-30 years old
Disqualifiers
• free from acute or chronic illness (cardiac, pulmonary, liver, or kidney abnormalities, cancer, uncontrolled hypertension, insulin- or non-insulin dependent diabetes or other known metabolic disorders)
do not take medications related to metabolism (i.e., statins, metformin, GLP-1 agonists)
free from orthopedic limitations (including any artificial joints)
currently smoke or participate in other forms of tobacco use.
Trial design
Design model
Crossover
Treatments tested in this trial
Decreased step count
BehavioralSubjects will walk less than 5,000 steps
Treatment groups
6 Participants
are divided into 2 treatment groupsGroup A: >8,500 steps the day prior to exericseActive comparator 1 intervention
Group B: <5,000 steps the day prior to exerciseExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Concentration of metabolites within the plasma
We will collect blood before and immediately after exercise. Plasma will be separated and sent for untargeted metabolomic analysis.
Time frame
Participants will complete the study within 6 weeks of enrollment.2
Concentration of proteins within the plasma
We will collect blood before and immediately after exercise. Plasma will be separated and sent for untargeted proteomic analysis.
Time frame
Participants will complete the study within 6 weeks of enrollment.Sponsors and contacts
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Source ClinicalTrials.gov