The Effects of VC Versus PC Ventilation on Cerebral and Respiratory Parameters in Patients Undergoing Laparoscopic Gynecologic Surgery

ConditionsAnesthesia Gynecologic Cancer Mechanical Ventilation Complication

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexFemale

Age18-70

SponsorUmraniye Education and Research Hospital

About this trial

The aim of the study was to determine whether the use of different mechanical ventilation modes in patients with Trendelenburg position and CO2 insufflation affects respiration and cerebral oxygenation due to postoperative atelectasis, and was to determine whether there was any hemodynamic effect.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

18-70 age

ASA 1-3

Disqualifiers

Under 18 years of age, over 70 years of age,

ASA IV,

history of severe chronic obstructive pulmonary disease (COPD, GOLD III or IV)

history of any thoracic surgery operation, need for thoracic drainage before surgery

Trial design

Design model

Parallel

Treatments tested in this trial

Mechanical Ventilation Mode
Procedure/Surgery
after intubation different ventilation mode (VC,PC,PC-VG)

Treatment groups

120 Participants

are divided into 3 treatment groups

Group A: ventilation mode during surgeryActive comparator 1 intervention

Group B: Pressure-controlled volume guaranteed mode (PC-VG) ventilationActive comparator 1 intervention

Group C: Pressure control mode (PC) ventilationActive comparator 1 intervention

Trial outcomes

Primary outcomes

pulmonary datas in laparoscopic gynecologic surgery.

peak airway pressure (minumum 40 cm H2O ,maksimum 40 cm H2O)

Time frame

one week

cerebral datas in laparoscopic gynecologic

NIRS (20% change from baseline value)

Time frame

one week

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Umraniye Education and Research Hospital

Lead sponsor

Source ClinicalTrials.gov

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