The Efficacy of Intrathecal Morphine Versus Intrathecal Morphine-Dexamethasone Combination in Cesarean Delivery

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-40
SponsorYuzuncu Yil University

About this trial

The Efficacy of Intrathecal Morphine Versus Intrathecal Morphine+Dexamethasone Combination added to bupivacaine in elective cesarean section under spinal anesthesia

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Patients scheduled for caesarean sections

Between 18-40 years

ASA II group

Those who will undergo spinal anesthesia

Disqualifiers

Those who prefer general anesthesia

Those who are outside the age range of 18-40

Those who are ASA III and above

Those with HT, DM, cardiac and respiratory diseases

Trial design

Design model

Parallel

Treatments tested in this trial

  • Group morphine

    Procedure/Surgery

    Group Morphine: Spinal anesthesia will be applied to patients who will undergo caesarean section using a combination of 2 ml (10 mg) bupivacaine + 0.1 ml (100 mcg) morphine + 0.5 ml saline

  • Group morfin+dexamethasone

    Procedure/Surgery

    Group morfin+dexamethasone: Spinal anesthesia will be applied to patients who will undergo a caesarean section using a combination of 2 ml (10 mg) bupivacaine + 0.1 ml (100 mcg) morphine + 0.5 ml (2 mg) dexamethasone

Treatment groups

120 Participants
are divided into 2 treatment groups
Group A: Group morfinActive comparator 1 intervention
Group B: Group morfin+dexamethasoneExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Postoperative nausea-vomiting

The incidence of postoperative nausea and vomiting will be scored from 0 to 3. No nausea or vomiting attacks will be graded as 0, a nausea attack that resolves without treatment will be graded as 1, recurrent nausea attacks that resolve with treatment will be graded as 2, and persistent nausea or vomiting attacks will be graded as 3.

Time frame
For 24 hours after surgery
2

Postoperative itching

The degree of pruritus will be assessed on a scale of 0 to 3, with 0 being categorized as no pruritus; 1 as mild pruritus; 2 as moderate pruritus; and 3 as severe pruritus.

Time frame
For 24 hours after surgery

Secondary outcomes

1

Intraoperative Mean Blood Pressure

Mean blood pressure will be measured every 5 minutes intraoperatively using a noninvasive method.

Time frame
Intraoperatively every 5 minutes
2

Intraoperative Heart Rate

Heart rate will be measured every 5 minutes intraoperatively using a noninvasive method

Time frame
Intraoperatively every 5 minutes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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