The Global Cardiovascular Risk Consortium
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversitätsklinikum Hamburg-Eppendorf
About this trial
The Global Cardiovascular Risk Consortium (GCVRC) brings together harmonized individual-level data from currently more than 2 million (anticipated: approximately 3 million) individuals across 133 cohorts, 40 countries, and 6 continents, with recruitment ongoing. The GCVRC examines the impact of classical cardiovascular risk factors-such as body-mass index, systolic blood pressure, non-high-density lipoprotein cholesterol, current smoking, and diabetes-on cardiovascular disease (CVD) and death from any cause worldwide.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
Participants with age below 18 years
No information on the outcome of interest
No information on the exposure of interest (CVD risk factors)
History of CVD at baseline
Trial population
The GCVRC uses harmonized individual-level data from currently more than 2 Mio individuals from 133 cohorts, 40 countries and 6 continents, categorized in 8 geographical regions - North America, Latin America, Sub-Saharan Africa, North Africa and the Middle East, Western Europe, Eastern Europe and Russia, Asia, and Australia. The database provides information on cardiovascular risk factors, including body-mass index, systolic blood pressure, non-high-density lipoprotein cholesterol, current smoking, and diabetes, as well as data on major cardiovascular outcomes and death.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
Cardiovascular disease (CVD)
Event rates of CVD and CVD subtypes: First fatal or non-fatal myocardial infarction, unstable angina, coronary revascularization, ischemic or hemorrhagic stroke, and cardiovascular or unclassifiable death. The type of outcome measurement varies across cohorts. CVD cases and subtypes are assessed by questionnaire information, national hospital discharge registry data, causes of death registry data or central death registries depending on the study protocol of the respective cohort studies.
Time frame
Median follow-up of 7-10 years2
Death from any cause
Number of deaths from any cause.
Time frame
Median follow-up of 7-10 yearsSponsors and contacts
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Source ClinicalTrials.gov