The Homburg Keratoconus Center (HKC)
ConditionKeratoconus
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorUniversität des Saarlandes
About this trial
Aim of this study is to conduct longitudinal and cross-sectional analyses about the corneal ectatic disease Keratoconus based on data obtained from Keratoconus patients in the Homburg Keratoconus Center (HKC).
The Homburg Keratoconus Center (HKC) was founded in 2010 and, up to now, comprises more than 3,000 Keratoconus patients. Topographic, tomographic and biomechanic characteristics of the disease are being analyzed with the intention to elucidate how the disease begins and develops during lifetime.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
All Keratoconus patients presenting in the department of ophthalmology, Saarland University Medical Center, Homburg, Saarland, Germany.
Disqualifiers
Patients without Keratoconus.
Trial population
Keratoconus patients of all ages presenting in the department of ophthalmology, Saarland University Medical Center, Homburg, Saarland, Germany, should be included.
Trial design
Design model
Cohort
Time perspective
Other
Treatments tested in this trial
Topographic, tomographic and biomechanical analysis.
Diagnostic testThe study is based upon data obtained during routine medical follow-ups using 1. the Pentacam high resolution (Oculus, Wetzlar, Germany) 2. the Corvis ST (Oculus, Wetzlar, Germany) 3. the Anterior-Segment Optical Coherence Tomograph (AS-OCT) Casia 2 (Tomey, Nagoya, Japan) 4. the Ocular Response Analyzer (Reichert Technologies, New York, USA).
Treatment groups
5,000 Participants
are divided into 1 treatment groupGroup A: Patients with Keratoconus1 intervention
Trial outcomes
Primary outcomes
1
An overview about development of anterior corneal curvature in Keratoconus disease during lifetime.
The anterior radius of curvature (ARC, 3mm zone) of Keratoconus patients as measured by the Pentacam high resolution (Oculus, Wetzlar, Germany) at different ages (according to: Belin MW and Duncan JK. Keratoconus: The ABCD grading system. Klin Monbl Augenheilkd. 2016; 233(6): 701-707) is put into relation to the age of the Keratoconus patients.
Time frame
01/01/2011-01/01/20192
An overview about development of posterior corneal curvature in Keratoconus disease during lifetime.
The posterior radius of curvature (PRC, 3mm zone) of Keratoconus patients as measured by the Pentacam high resolution (Oculus, Wetzlar, Germany) at different ages (according to: Belin MW and Duncan JK. Keratoconus: The ABCD grading system. Klin Monbl Augenheilkd. 2016; 233(6): 701-707) is put into relation to the age of the Keratoconus patients.
Time frame
01/01/2011-01/01/20193
An overview about development of the thinnest corneal pachymetry in Keratoconus disease during lifetime.
The thinnest corneal pachymetry of Keratoconus patients as measured by the Pentacam high resolution (Oculus, Wetzlar, Germany) at different ages (according to: Belin MW and Duncan JK. Keratoconus: The ABCD grading system. Klin Monbl Augenheilkd. 2016; 233(6): 701-707) is put into relation to the age of the Keratoconus patients.
Time frame
01/01/2011-01/01/20194
An overview about development of the best corrected distance visual acuity in Keratoconus disease during lifetime.
The best corrected distance visual acuity of Keratoconus patients as raised as part of the clinical examination at different ages (according to: Belin MW and Duncan JK. Keratoconus: The ABCD grading system. Klin Monbl Augenheilkd. 2016; 233(6): 701-707) is put into relation to the age of the Keratoconus patients.
Time frame
01/01/2011-01/01/2019Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Universität des Saarlandes
Lead sponsor
University Hospital, Saarland
Sponsor institution
Source ClinicalTrials.gov