The Human Trisome Project
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age6-89
SponsorUniversity of Colorado, Denver
About this trial
The Human Trisome Project will significantly increase the speed of Down syndrome research and the understanding of associated medical conditions. Its biobank will provide de-identified samples to research.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
has Down syndrome (any type)
does not have Down syndrome
Disqualifiers
Prisoners
Wards of the state
Trial population
Individuals with Down syndrome, individuals related to someone with Down syndrome or of the general population who do not have a relationship to Down syndrome.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
2,500 Participants
are grouped into 2 trial groupsGroup A: Those with trisomy 21
Group B: Controls
Trial outcomes
Primary outcomes
1
Number of Participants and Controls Enrolled in Biobank
Create biobank of blood cells and plasma, saliva, mouth swab, urine, stool, and induced pluripotent stem cells (iPSC) cells for use in approved research projects.
Time frame
5 yearsSecondary outcomes
1
Number of Clinical Records Available for Approved Research Purposes
Create a database of clinical information to pair with biological samples listed above.
Time frame
5 years2
Multidimensional Sample Characterization
Characterize biological samples with multidimensional cellular and molecular analyses to generate the most thoroughly characterized set of samples from individuals with Down syndrome in the world.
Time frame
5 yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
University of Colorado, Denver
Lead sponsor
Linda Crnic Institute for Down Syndrome
Collaborator
National Center for Advancing Translational Sciences (NCATS)
Collaborator
GLOBAL Down Syndrome Foundation
Collaborator
Anna and John J. Sie Foundation
Collaborator
Source ClinicalTrials.gov