The Impact of Light, Electrical, and Magnetic Neuroregulation Interventions on Sleep-wake Disorders

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age8-75
SponsorSecond Affiliated Hospital of Soochow University

About this trial

Carry out precise and effective neuromodulation interventions, and develop new neuromodulation technologies for sleep disorders. Use phototherapy, transcranial electrical/magnetic stimulation and other therapies to conduct self-controlled intervention studies on insomnia, narcolepsy, and rapid eye movement sleep behavior disorder .

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Patients with major neurological diseases such as multi-infarct dementia, Huntington's disease, normal pressure hydrocephalus, brain tumors, progressive supranuclear palsy, epilepsy, subdural hematoma, multiple sclerosis, or those who have sustained neurological dysfunction or known structural brain abnormalities after significant head trauma are excluded.

A history of major depressive disorder or bipolar disorder within the past year, as defined in DSM-IV criteria. A history of schizophrenia (meeting DSM-IV criteria).

History of severe drug or alcohol abuse within the past year;

Any significant systemic illness or unstable medical condition that may make it difficult to comply with the protocol, such as severe autoimmune diseases or a history of cancer.

Trial design

Design model

Single group

Treatments tested in this trial

  • Transcranial Magnetic Stimulation

    Device

    repetitive transcranial magnetic stimulation, or transcranial direct current stimulation, or daytime timed bright light exposure

Treatment groups

20 Participants
are divided into 1 treatment group
Group A: Intervention GroupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Objective sleep indicators and clinical sleep-related scales

Time frame
From enrollment to the end of treatment at 4 weeks

Secondary outcomes

1

Resting-state electroencephalogram, resting-state functional magnetic resonance imaging, blood biochemical indicators

Time frame
From enrollment to the end of treatment at 4 weeks

Other outcomes

Sponsors and contacts

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