This study is a retrospective analysis of a large-scale multicentre prospective cohort study that investigates the impact of preoperative depression on the incidence of postoperative delirium among elderly Chinese patients undergoing non-cardiac major surgery.
1. Age ≥ 65 years, both genders 2. Elective non-cardiac major surgery 3. Completed preoperative depression assessment (PHQ-9) 4. Completed postoperative delirium assessment (3D-CAM)
1. History of neurological or psychiatric disorders or use of neuropsychiatric medications 2. Impaired cognitive function or inability to complete preoperative follow-up 3. Transferred to ICU postoperatively 4. Missing delirium outcome data
Elderly patients (aged ≥ 65 years) who completed the anxiety and depression assessment before elective non-cardiac major surgery were included in this study
Cohort
Prospective
Not listed
Postoperative Delirium
Postoperative delirium (POD) incidence was assessed using the 3-minute Diagnostic Interview for CAM (3D-CAM). The 3D-CAM is a validated tool for the detection of delirium in older adults. It evaluates four key features: acute onset and fluctuating course, inattention, disorganized thinking, and altered level of consciousness. If the patient was discharged, follow-up was conducted by telephone or email.
Postoperative Acute Pain
Postoperative acute pain was assessed using the Numerical Rating Scale (NRS). The NRS is an 11-point scale ranging from 0 (no pain) to 10 (worst possible pain).
Postoperative Pulmonary Infection
Postoperative pulmonary infection was assessed through physical examination and laboratory tests (chest X-ray, white blood cell count, etc.).
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Chinese PLA General Hospital
Lead sponsor
Beijing Tsinghua Changgeng Hospital
Collaborator
Peking University First Hospital
Collaborator
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Collaborator
Xiangya Hospital of Central South University
Collaborator
Beijing Anzhen Hospital
Collaborator
Central South University
Collaborator
Peking University People's Hospital
Collaborator
Zhejiang University
Collaborator
Fudan University
Collaborator
Sun Yat-sen University
Collaborator
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Collaborator
China-Japan Friendship Hospital
Collaborator
The Affiliated Hospital Of Guizhou Medical University
Collaborator
First Affiliated Hospital of Xinjiang Medical University
Collaborator
First Affiliated Hospital of Guangxi Medical University
Collaborator
Taihe Hospital
Collaborator
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