The Impact of Preoperative Depression on Postoperative Delirium in Elderly Chinese Patients: A Retrospective Multicenter Observational Study

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65-100
SponsorChinese PLA General Hospital

About this trial

This study is a retrospective analysis of a large-scale multicentre prospective cohort study that investigates the impact of preoperative depression on the incidence of postoperative delirium among elderly Chinese patients undergoing non-cardiac major surgery.

Eligibility criteria

Qualifiers

1. Age ≥ 65 years, both genders 2. Elective non-cardiac major surgery 3. Completed preoperative depression assessment (PHQ-9) 4. Completed postoperative delirium assessment (3D-CAM)

Disqualifiers

1. History of neurological or psychiatric disorders or use of neuropsychiatric medications 2. Impaired cognitive function or inability to complete preoperative follow-up 3. Transferred to ICU postoperatively 4. Missing delirium outcome data

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

8,000 Participants
are grouped into 2 trial groups

Locations

This trial has no locations

Sponsors and collaborators

Chinese PLA General Hospital

Lead sponsor

Beijing Tsinghua Changgeng Hospital

Collaborator

Peking University First Hospital

Collaborator

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

Collaborator

Xiangya Hospital of Central South University

Collaborator

Beijing Anzhen Hospital

Collaborator

Central South University

Collaborator

Peking University People's Hospital

Collaborator

Zhejiang University

Collaborator

Fudan University

Collaborator

Sun Yat-sen University

Collaborator

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Collaborator

China-Japan Friendship Hospital

Collaborator

The Affiliated Hospital Of Guizhou Medical University

Collaborator

First Affiliated Hospital of Xinjiang Medical University

Collaborator

First Affiliated Hospital of Guangxi Medical University

Collaborator

Taihe Hospital

Collaborator