About this trial
This is a prospective observation cohort investigation. Patients, that is participants, undergoing primary functional rhinoplasty will be evaluated in terms of measuring capillary blood lactic acid concentration in the nasal skin-soft tissue envelope immediately after the procedure and 7 days after the procedure.
The aim of our study is to test whether or not different rhinoplasty approaches and volume of the used autologous cartilage grafts impact the nasal skin-soft tissue metabolism.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Adult patients undergoing primary functional rhinoplasty who comply with the study
Adult patients undergoing primary functional rhinoplasty who have singed the informed consent, previously approved by the ethics commitee.
Disqualifiers
patients with previous surgical procedures to the nose
patients with greater previous injury or burns to the nasal skin
patients with autoimmune skin conditions
patients with significant cardiovascular diseases
Trial population
All patients between 18 and 80 years of age, scheduled for primary functional rhinoplasty, who are willing to comply with the study and sign the informed consent, previously approved by the ethics commitee.
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Difference of capillary blood lactic acid concentration in the nasal skin-soft tissue envelope depending on the rhinoplasty approach
In participants undergoing primary functional rhinoplasty, the capillary blood lactic acid concentration from the skin-soft tissue envelope will be assessed by using Statstrip lactate measuring device and Statstrip test strips immediately after the procedure and 7 days after the procedure.
Correlation between the used autologous cartilage graft volume and lactic acid concentration in the nasal skin-soft tissue envelope
In the same participants undergoing different rhinoplasty approach, the volume of the used autologous cartilage grafts will be measured by using water displacement method, and this result will be correlated with the capillary blood lactic acid concentration from the skin-soft tissue envelope.
Locations
Sponsors and contacts
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This trial is not recruiting at the moment. You can still explore other options: