The Incidence, Clinical Characteristics and Outcome of Infective Endocarditis Among Intravenous Drug Abusers Versus Non-Drug Abusers.

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssiut University

About this trial

We aim to describe the incidence of IVDA among patients presented with IE, describe their clinical, psychiatric and microbiological characteristics in comparison to non - IVDA, as well as the rate and types of complications and outcome, and responsiveness to medical treatment or surgical intervention.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adult Patients (>18 years) with definite or possible IE.

Disqualifiers

Patients with rejected diagnosis of infective endocarditis after workup, according to modified Duke's criteria.

Trial population

Patients admitted to Assiut University Heart Hospital with definite or possible Infective endocarditis

Trial design

Design model

Other

Time perspective

Cross-sectional

Treatments tested in this trial

  • Echocardiography, Urine analysis , blood culture

    Diagnostic test

    All patients will be investigated by ECG, Urine analysis, blood culture , Echocardiography

Treatment groups

46 Participants
are divided into 2 treatment groups
Group A: IE in IV drug abusers1 intervention
Group B: IE in non- IV drug abusers1 intervention

Trial outcomes

Primary outcomes

1

The incidence of IVDA among IE patients

Report the incidence of IVDA among IE patients, describe their clinical and microbiological characteristics comparison to the IE in non - IVDA.

Time frame
Baseline
2

The complications of IVDA among IE patients

Report the rates and types of complications

Time frame
Baseline

Secondary outcomes

1

The psychiatric characteristics of the addict group

This will be done by psychiatric questionnaires: -Addiction Severity Index questionnaire to measure severity of the addiction on the patient

Time frame
Baseline
2

The Withdrawal symptoms of the study group

This will be done by psychiatric questionnaires: -Withdrawal symptoms questionnaire that occur to the patient after stop of the addiction

Time frame
Baseline
3

The psychiatric characteristics of the study group

This will be done by psychiatric questionnaires: -Symptom Check List 90 to measure other comorbidities

Time frame
Baseline
4

The personality characteristics of the study group

This will be done by psychiatric questionnaires: -Eysenck Personality questionnaire to measure personality.

Time frame
Baseline

Other outcomes

Sponsors and contacts

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