The Influence of Prone Position for Spinal Surgery on Visual Acuity

ConditionVision; Disorder, Loss

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-65

SponsorUniversity Hospital Hradec Kralove

About this trial

This study investigated the effect of desflurane and propofol anesthesia on visual acuity in patients in prone position for spinal surgery. Many trials have investigated the effects of different anesthetic agents on intraocular pressure, propofol may reduce intraocular pressure more than other intravenous anesthetics.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Glasgow Coma scale 15

American Society of Anesthesiologists (ASA) Physical Status Classification System I-III

spinal surgery in duration less than 3 hours

sinus rhythm

Disqualifiers

postoperative artificial ventilation

serious neurological disease

lung disease with hypercapnia

propofol allergy

Trial design

Design model

Parallel

Treatments tested in this trial

Desflurane Group
Procedure/Surgery
General anesthesia will be held using desflurane in end- tidal concentration according to target value of entropy levels (between 40 and 60).
Propofol Group
Procedure/Surgery
General anesthesia will be held using Schnider effect model for propofol (target control anesthesia). Titration will be done according to target value of entropy levels (between 40 and 60).

Treatment groups

60 Participants

are divided into 2 treatment groups

Group A: Desflurane GroupExperimental treatment 1 intervention

Group B: Propofol GroupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

Visual injury

worsening of test for visual acuity (Rodenstock)

Time frame

48 hours

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University Hospital Hradec Kralove

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: