The Long-term Effect of Artificial Intelligence-assisted Colonoscopy on Risk of Metachronous Advanced Colonic Lesion

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorThe University of Hong Kong

About this trial

The goal of this prospective study is to to evaluate the prevalence of metachronous advanced colonic lesions in subsequent surveillance colonoscopies in patients who had previously undergone AI-assisted colonoscopy to conventional colonoscopy examinations.

The main question it aims to answer is whether employing AI-assisted colonoscopy can decrease the likelihood of metachronous advanced colonic lesions during subsequent surveillance colonoscopies.

Researchers will compare patient who undergo conventional colonoscopy in previous colonoscopy to see if AI-assisted colonoscopy can decrease the likelihood of metachronous advanced colonic lesions during subsequent surveillance colonoscopies. Participants will undergo surveillance colonoscopy to assess the presence of metachronous advanced colonic lesion

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Eligible participants are those who were previously enrolled and completed our randomized controlled trial comparing AI-assisted and conventional colonoscopy

Disqualifiers

In addition to the baseline exclusion criteria of the index trial, patients who were found to have inflammatory bowel disease, colorectal cancer and underwent bowel resection would be excluded. Similar to index trial, patients who have developed severe comorbid illnesses that make surveillance colonoscopy and polypectomy unsafe, or become unable to provide informed consent for trial participation would also be excluded

Trial design

Design model

Single group

Treatments tested in this trial

  • Suveillance colonoscopy

    Procedure/Surgery

    Surveillance colonoscopy

Treatment groups

404 Participants
are divided into 1 treatment group
Group A: Surveillance colonoscopyOther 1 intervention

Trial outcomes

Primary outcomes

1

the cumulative risk of metachronous advanced colonic lesions

the cumulative risk of metachronous advanced colonic lesions

Time frame
Three years

Secondary outcomes

1

cumulative risk of non-advanced metachronous adenoma and serrated lesions

cumulative risk of non-advanced metachronous adenoma and serrated lesions

Time frame
three years
2

mean number of metachronous advanced colonic lesions

mean number of metachronous advanced colonic lesions

Time frame
three years
3

mean number of metachronous adenomas, advanced adenomas, serrated lesions, and advanced serrated lesions

mean number of metachronous advanced colonic lesions, adenomas, advanced adenomas, serrated lesions, and advanced serrated lesions

Time frame
three years

Other outcomes

Sponsors and contacts

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