The Lymphocytic Infiltrate of Lung Tumors.
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorScientific Institute San Raffaele
About this trial
The study is configured as a monocentric observational transversal biological study.
The main objective of the study is the reconstruction of the molecular organization of tumors of the thoracic cavity, in particular non-small cell lung cancer (NSCLC).
The study involves the collection of clinical data and biological material (blood and tumor tissue) from 70 subjects diagnosed with thoracic tumors.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Ability to provide informed consent;
Men and women over the age of 18;
Patients candidates for surgical treatment diagnosed with thoracic tumors
Disqualifiers
Previous chemotherapy for any cancer within the last 6 months;
Pregnant and/or breastfeeding women;
Immunosuppressive state (states of immunosuppression or ongoing immunosuppressive/immunomodulatory treatments)
Trial population
The population is made up of patients diagnosed with thoracic cancer, candidates for surgical resection for the disease.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
LYMPHOCYTE ISOLATION
the collection of lymphocytes, and their sequencing and analysis of differentially expressed genes.
Time frame
from enrollment in the study to surgery at 15 daysSecondary outcomes
1
Lymphocyte gene expression
Analysis of gene expression and translational activity of lymphocyte cells (CD4+)
Time frame
from surgery to processing within 48 hoursSponsors and contacts
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Source ClinicalTrials.gov