The Myeloid Neoplasms Biology and Outcome Project
ConditionMyeloid Neoplasm
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital Heidelberg
About this trial
The Myeloid Neoplasms Biology and Outcome Project (MyBOP) aims to establish a registry study for patients with myeloid neoplasms. It integrates clinical data, biological samples, socio-demographic information, long-term follow-up and patient reported outcomes in a structured manner for scientific purposes.
The ultimate benefits are:
1. Improvement of evidence-based clinical management of patients with myeloid neoplasms through better understanding of the course of disease and prognostic and predictive parameters 2. Direct access to new and personalized treatment approaches through recruitment into clinical studies based on the myeloid neoplasms study platform 3. Quality assurance of participating centers by evaluating and comparing clinical outcomes and side effects of the MyBOP patients with published data.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Suspected or proven diagnosis of Myeloid Neoplasms according to the WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues
Age ≥18 years
Ability to understand the nature and individual consequences of the registry
Written informed consent
Disqualifiers
None
Trial population
the patient cohort will be selected from the University Hospital Heidelberg.
Trial design
Design model
Other
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
median overall survival (mOS)
Time period of survival from date of diagnosis of myeloid neoplasy
Time frame
5 years2
overall survival (mOS)
Time period of survival from date of diagnosis of myeloid neoplasy
Time frame
10 years3
event free survival (EFS)
Time period of event free survival from date of diagnosis of myeloid neoplasy
Time frame
5 years4
progression free survival (PFS)
Time period of progression survival from date of diagnosis of myeloid neoplasy
Time frame
5 yearsSecondary outcomes
1
Questionnaire for the health- related quality of life QLQ-C30
Standardized Quality of Life Assessment, Higher values are better
Time frame
5 years2
Questionnaire for physical, cognitive and emotional aspects of cancer-related fatigue QLQ-FA12
Standardized Quality of Fatigue, Higher values are worse
Time frame
5 years3
Questionnaire for anxiety and depression PHQ-4
Standardized Quality of anxiety and depression, Higher values are worse
Time frame
5 years4
Functional Assessment of Cancer Therapy Fact-Cog
Standardized Quality of cognitive function, Higher values are better
Time frame
5 yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov