The Next Step Towards the Elimination of Iodine Deficiency and Preventable Iodine-related Disorders in Europe

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age13-17
SponsorEUthyroid

About this trial

In the EUthyroid2 intervention, measures are being developed and implemented in educational settings across the UK, Germany, Slovenia, the Republic of Cyprus, Bangladesh, and Pakistan to effectively raise awareness of the risks associated with iodine deficiency. Each participating country will employ three measurement points. The intervention will be tailored to the specific contextual characteristics of each implementation site. A process evaluation utilizing a convergent parallel mixed methods design will be conducted, involving surveys of students and teachers, as well as semi-structured interviews.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

sufficient language skills to understand the study information, informed consent

Disqualifiers

none

Trial design

Design model

Single group

Treatments tested in this trial

  • Experimental: Intervention group

    Other intervention

    Educational materials: Iodine Feedback Tool, lecture on the topic of iodine and health, booklet, exercises, group assignments and a webpage This is a pre/post intervention with no control group.

Treatment groups

4,500 Participants
are divided into 1 treatment group
Group A: Teaching programme on iodineExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Change in awareness

1\. Change in awareness of iodine and iodine deficiency: Difference in iodine awareness is measured by an iodine awareness questionnaire. The scoring ranges from 1 to 22 points with higher scores indicating a better outcome of awareness.

Time frame
T1 (baseline) to T2 (2-4 weeks) and T3 (6-8 months) in students (13-17 years)

Secondary outcomes

1

Changes between teaching modalities

Differences in iodine awareness between students taught module A vs module A+B vs module A+C vs module A+B+C. Changes in iodine awareness are assessed by the iodine awareness questionnaire. The scoring ranges from 1 to 22 points with higher scores indicating a better outcome of awareness.

Time frame
T1 (baseline) to T2 (2-4 weeks) and T3 (6-8 months)
2

Changes in vocational schools, high- and secondary schools

Differences in iodine awareness between students in vocational schools vs high schools vs secondary schools. Changes in iodine awareness are assessed by the iodine awareness questionnaire. The scoring ranges from 1 to 22 points with higher scores indicating a better outcome of awareness.

Time frame
T1 (baseline) to T2 (2-4 weeks) and T3 (6-8 months)
3

Change between age groups and gender distinctions

Differences in iodine awareness between girls vs boys. Changes in iodine awareness are assessed by the iodine awareness questionnaire. Differences in iodine awareness between 13-year-olds vs 14-year-olds vs 15-year-olds vs 16-year-olds vs 17-year-olds. Changes in iodine awareness are assessed by the iodine awareness questionnaire. The scoring ranges from 1 to 22 points with higher scores indicating a better outcome of awareness. Gender and age will be self-reported in a socio-demographic questionnaire.

Time frame
T1 (baseline) to T2 (2-4 weeks) and T3 (6-8 months)
4

Change in iodine intake

Dietary iodine intake is assessed through a food frequency questionnaire (FFQ), covering five main categories (cow's milk, fish, eggs, supplements, and salt) and regional components in each country. Each category is scored based on frequency (portions per day, week, or month), and individual sources are analyzed for iodine intake. For example, taking supplements 5-7 times a week or consuming a combination of multiple sources of cow's milk, fish and eggs a week may suggest sufficient intake. Regional differences are also considered, as salt is an iodine source in countries like Pakistan and Bangladesh, but not in the UK or Norway. The number of iodine sources will be compared before and after the intervention within each country, with a higher number of sources indicating a higher iodine intake). The number will differ according to the number of sources in each country.

Time frame
T1 (baseline) to T2 (2-4 weeks) and T3 (6-8 months)

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

EUthyroid

Lead sponsor

EU Horizon

Collaborator

UK Research and Innovation

Collaborator