The Relationship Between Arterial Stiffness and Pulmonary and Extrapulmonary Features in Ankylosing Spondylitis

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-85
SponsorKirsehir Ahi Evran Universitesi

About this trial

The aim of this study was to investigate the relationship between arterial stiffness and pulmonary and extrapulmonary features in patients with ankylosing spondylitis.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Diagnosis of ankylosing spondylitis according to ASAS diagnostic criteria

Being aged 18-65

Stable medication use for at least 3 months

Voluntary participation in the study

Disqualifiers

Having uncontrolled cardiopulmonary disease

Being pregnant

Having undergone recent surgery

Presence of malignancy

Trial population

Patients followed up with a diagnosis of ankylosing spondylitis will be included.

Trial design

Design model

Case-only

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

25 Participants
are grouped into 1 trial group
Group A: Ankylosing spondylitis

Trial outcomes

Primary outcomes

1

Arterial stiffness

It will be evaluated with brachial pulse waves.

Time frame
1st day
2

Respiratory muscle strength

Maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) will be measured using a portable mouth pressure device.

Time frame
1st day
3

Respiratory muscle endurance

This will be evaluated with increased workload testing.

Time frame
1st day
4

Exercise capacity

Exercise capacity will be assessed with 6 minute walk test.

Time frame
1st day

Secondary outcomes

1

Physical activity

Physical activity level will be evaluated using International Physical Activity Questionnaire-Short form

Time frame
1st day
2

Forced vital capacity

Forced vital capacity (FVC) will be assessed using spirometry.

Time frame
1st day
3

Forced expiratory volume in one second

Forced expiratory volume in one second (FEV1) will be assessed using spirometry.

Time frame
1st day
4

Forced expiratory volume in one second/forced vital capacity ratio

Forced expiratory volume in one second/forced vital capacity ratio will be assessed using spirometry.

Time frame
1st day

Other outcomes

Sponsors and contacts

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