About this trial
The aim of this study was to investigate the relationship between arterial stiffness and pulmonary and extrapulmonary features in patients with ankylosing spondylitis.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Diagnosis of ankylosing spondylitis according to ASAS diagnostic criteria
Being aged 18-65
Stable medication use for at least 3 months
Voluntary participation in the study
Disqualifiers
Having uncontrolled cardiopulmonary disease
Being pregnant
Having undergone recent surgery
Presence of malignancy
Trial population
Patients followed up with a diagnosis of ankylosing spondylitis will be included.
Trial design
Case-only
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Arterial stiffness
It will be evaluated with brachial pulse waves.
Respiratory muscle strength
Maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) will be measured using a portable mouth pressure device.
Respiratory muscle endurance
This will be evaluated with increased workload testing.
Exercise capacity
Exercise capacity will be assessed with 6 minute walk test.
Secondary outcomes
Physical activity
Physical activity level will be evaluated using International Physical Activity Questionnaire-Short form
Forced vital capacity
Forced vital capacity (FVC) will be assessed using spirometry.
Forced expiratory volume in one second
Forced expiratory volume in one second (FEV1) will be assessed using spirometry.
Forced expiratory volume in one second/forced vital capacity ratio
Forced expiratory volume in one second/forced vital capacity ratio will be assessed using spirometry.
Sponsors and contacts
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