The Relationship Between Hypotension and Tissue O2 in Invasive Eadyn During Anesthesia Induction in Open Heart Surgery

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-90
SponsorHaseki Training and Research Hospital

About this trial

Our aim is to identify patients who may experience hypotension during anesthesia induction. Intraoperative hemodynamic stability plays an important role in tissue oxygenation. Although the duration of hypotension can be kept short with the necessary interventions, it is important that hypotension is predictable in order to prevent intraoperative complications and postoperative organ damage.

40 patients scheduled for open heart surgery will be monitored from one minute before anesthesia is administered until ten minutes after. Patients will be divided into two groups based on the presence or absence of hypotension during the monitoring period. All patients will be monitored according to a standardized procedure. Demographic data, non-invasive and invasive hemodynamic parameters, primarily Eadyn, and cerebral and renal tissue saturation data will be collected. Moreover, vasopressor administration in response to hypotension will be recorded.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Presence of arrhythmia (atrial fibrillation or frequent premature beats)

Severe valvular heart disease (aortic or mitral stenosis/insufficiency)

Severe heart failure (EF < 40%)

Congenital heart disease

Trial population

Patients diagnosed with coronary artery disease who were scheduled to undergo elective open-heart surgery were included in the study.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • mostcare hemodynamic monitor

    Device

    Invasive hemodynamic variables including dynamic arterial elastance (Eadyn), stroke volume variation (SVV), pulse pressure variation (PPV), cardiac index (CI), oxygen delivery (DO₂), and cardiac power output (CPO) were obtained using the MostCare monitor.

  • Masimo NIRS

    Device

    Cerebral and renal tissue oxygen saturation(rso2) values were measured using the Masimo device.

  • Hemodynamic Measurements on Standart Monitoring

    Device

    Heart rate and peripheral oxygen saturation were measured using standard noninvasive monitoring.

Treatment groups

40 Participants
are divided into 2 treatment groups
Group A: Hypotension Group3 interventions
Group B: Non-hypotension Group3 interventions

Trial outcomes

Primary outcomes

1

Eadyn

Dynamic Arterial Elastance

Time frame
Perioperative
2

rso2

Cerebral and Kidney Regional Saturation

Time frame
Perioperative
3

Intraoperative hypotension

Explanatory outcome

Time frame
perioperative

Secondary outcomes

Other outcomes

Sponsors and contacts

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