The REMINDER4Care Program for Older Adults Supported by Residential and Daycare Facilities
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age65+
SponsorUniversity of Coimbra
About this trial
Dementia incidence is rising, posing a public health challenge, but 45% of cases can be prevented by addressing modifiable risk factors. Multidomain trials show that lifestyle changes can improve cognitive function and reduce dementia risk (like the FINGER trial). The REMINDER program, a Portuguese-based dementia risk reduction protocol, was developed for community-dwelling older adults aged 55 and above. However, older adults in Residential and Daycare Facilities (RDF) have distinct needs that demand program adaptation to ensure its relevance and effectiveness. In addition, more studies are needed to evaluate the impact of multidomain interventions with older adults in RDF.
To address these challenges, the REMINDER4Care program was developed as a tailored, multidomain intervention to reduce dementia risk. It emphasizes social and cognitive engagement and advances its adaptation and evaluation in Residential and Daycare Facilities (RDF). To assess efficacy, the investigators will perform a Randomized Controlled Trial.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Aged 65 years and older
RDF users
Elementary reading and writing skills
Disqualifiers
Have a clinical diagnosis of dementia and/or Mini-Mental State Examination (MMSE) scores below the cutoff for the presence of dementia (MMSE < 22-27, depending on education level)
Have a psychiatric or neurological condition that impairs cognition in the long term
Have sensory and functional deficits that compromise their participation in the neuropsychological assessment and throughout the intervention sessions
Trial design
Design model
Sequential
Treatments tested in this trial
REMINDER4Care
Other interventionREMINDER4Care was an adapted version of the original REMINDER program, tailored to the characteristics, needs, and interests of older adults in RDF. The REMINDER4Care intervention includes 20 face-to-face group sessions, each approximately 60 to 75 minutes, held twice a week over ten weeks. This program aims to optimize memory, attention, executive function, and emotional regulation while promoting lifestyle habits that protect the aging brain. The sessions include brain health education, cognitive exercises, compensatory memory strategies, training for managing personally relevant goals (with goal setting), and stress management techniques (compassion-based therapies, relaxation methods, and mindfulness). Social support and emotion regulation strategies (like attention management, positive cognitive reappraisal, and reframing speech) were included to address psychosocial risk factors like stress, social isolation, and depression.
Treatment groups
100 Participants
are divided into 2 treatment groupsGroup A: REMINDER4Care interventionExperimental treatment 1 intervention
Group B: Waiting-list groupNo intervention 0 interventions
Trial outcomes
Primary outcomes
1
Screening
Participants' sociodemographic (e.g., age, marital status, education level) and clinical (presence of medical diagnosis, current medication, sensory issues, mobility deficits, substance use, and hospitalization).
Time frame
Screening2
Screening
Dementia risk was assessed using the Lifestyle for BRAin health (LIBRA) score, which ranges from -2.1 to 10.6, with higher scores indicating a greater risk of developing dementia.
Time frame
Screening3
Cognitive status
Global cognition was assessed using Addenbrooke's Cognitive Examination - Revised (ACE-R), a scale with scores ranging from 0 to 100, where higher scores indicate better cognitive functioning.
Time frame
Screening and 1-week and 3-months post-intervention4
Mood status
Depressive Symptoms: Assessed using the Geriatric Depression Scale (GDS-30), a 30-item scale with scores ranging from 0 to 30, where higher scores indicate greater depressive symptoms.
Time frame
Screening and 1-week and 3-months post-interventionSponsors and contacts
Click on the lead sponsor to view all of their trials.
University of Coimbra
Lead sponsor
Fundação para a Ciência e a Tecnologia
Collaborator
Source ClinicalTrials.gov