The Research About Acute Compartment Syndrome
ConditionAcute Compartment Syndrome
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorHebei Medical University Third Hospital
About this trial
Acute compartment syndrome (ACS) is defined as a clinical entity originated from trauma or other conditions, and remains challenging to diagnose and treat effectively. Threre is the controversy in diagnosing, treating ACS. It was found that there was no criterion about the ACS, and result unnecessary osteotomy. The presence of clinical assessment (5P) always means the necrosis of muscles and was the most serious or irreversible stage of ACS. Besides pressure methods, the threshold of pressure identifying ACS was also controversial.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Fracture patients with Schatzker V and VI,
Who were older than eighteen years.
Disqualifiers
The exclusion criteria were pathologic, extra-articular proximal tibial fracture,
Patients who was eighteen years or younger.
Patients treated with other implant,
underwent conservative management were also excluded.
Trial population
The severe tibial plateau (Ⅴand Ⅵ according to Schatzker's classification) in our hospital who will be treated with open internal fixation in our hospital
Trial design
Design model
Case-control
Time perspective
Prospective
Treatments tested in this trial
fasciotomy
Procedure/Surgeryif it was suspected with ACS, the fasciotomy was conducted. but if the blister observed, it means decreased conmpartment sydrome. therefore, the blister observed can avoid unnecessary fasciotomy to patients suspected with ACS
Treatment groups
80 Participants
are divided into 2 treatment groupsGroup A: fractures with blister appeared1 intervention
Group B: fractures without blister appeared1 intervention
Trial outcomes
Primary outcomes
1
injury mechanism
The relative data was collected about injury mechanism such as high falling accident, traffic accident, fall from standing height,Crushing
Time frame
up to 1 weeks2
the time when the blister appeared
The relative data was collected about the time when the blister appeared after injury
Time frame
up to 4 weeks3
time to reconstructive surgery
The relative data was collected about time to reconstructive surgery
Time frame
time to when the surgery was conducted after 2 weeks4
union time
The relative data was collected about union time
Time frame
through study completion, an average of 1 yearSecondary outcomes
1
CK levels
CK levels
Time frame
through hospitalization completion, an average of 1 month2
chloride levels
chloride levels
Time frame
through hospitalization completion, an average of 1 month3
UREA levels
UREA levels
Time frame
through hospitalization completion, an average of 1 monthOther outcomes
1
LKS score
Lysholm knee score
Time frame
through study completion, an average of 1 year2
VAS scores
visual analogue scale
Time frame
through study completion, an average of 1 yearSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov