The Role of Autoantibodies Against G-protein Coupled Receptors in Obesity

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-60
SponsorClaus Bogh Juhl

About this trial

The purpose of this study is to explore if GPCR-autoantibodies:

1. are pressent in people living with obesity, and are associated with degree of obesity 2. if it is associated with obesity related diseases

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Inhabitant in the Region of Southern Denmark

BMI above 30kg/m2

age between 18 and 60 years.

Disqualifiers

individuals previously treated with GLP-1RA medication for any indication

Individuals who have previously undergone bariatric surgery

Individuals with type 1 diabetes

Trial population

The South Danish Obesity Initiative (SDOI) cohort. This is an ongoing clinical initiative offering screening of a broad panel of obesity related diseases to individuals with BMI above 30 kg/m² and age between 18 and 60 years. People are referred from their general practitioners or from hospital departments and undergo screening for diabetes, dyslipidemia, obstructive sleep apnea, metabolic associated steatohepatitis and hypertension. In addition, a cohort of people with BMI 18.5 to 30 kg/m² has been assessed with an identical screening program with the purpose of serving as a control group. Only participants who gave informed consent to use their data for research purposes are included in this study.

Trial design

Design model

Cohort

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

160 Participants
are grouped into 1 trial group
Group A: The South Danish Obesity Initiative (SDOI)

Trial outcomes

Primary outcomes

1

Exploring the pressence and role of GPCR-autoantibodies in obesity

explore the pressence of GPCR-autoantibodies in people living with obesity, and if there is any association with the degree of obesity

Time frame
At the time of enrolement

Secondary outcomes

1

Exploring the association between GPCR-autoantibodies and obesity related diseases

explore if the pressence of GPCR-autoantibodies is associated with obesity related diseases (pre-diabetes, type 2 diabetes and metabolic syndrome) in people living with obesity

Time frame
At the time of enrolment

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Claus Bogh Juhl

Lead sponsor

Esbjerg Hospital - University Hospital of Southern Denmark

Sponsor institution

This trial is not recruiting at the moment. You can still explore other options: