The Role of Blood Perfusion in Cervical Cancer, Cervical Intraepithelial Neoplasm and Ovarian Cancer Patients

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
AgeNot listed
SponsorFar Eastern Memorial Hospital

About this trial

This study will elucidate the role of 3D transvaginal ultrasound in assessing (1) cervical vascularity and blood flow in patients with cervical cancer and cervical intraepithelial neoplasm, and (2) tumor vascularity and blood flow in patients with ovarian cancer.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Adult women who have had a normal cervical smear within the past three years and have no other gynecological cancers (control group).

Adult women with cervical cancer or precancerous lesions.

Adult women suspected of having ovarian cancer, fallopian tube cancer, or peritoneal cancer before surgery.

Disqualifiers

Patients who cannot cooperate with vaginal or abdominal 3D ultrasound scans.

Trial population

Women with cervical cancer, cervical intraepithelial neoplasm, ovarian cancer, and the disease-free control

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

  • Doppler ultrasound

    Diagnostic test

    3D doppler ultrasound to measure VI, FI, VFI.

Treatment groups

100 Participants
are divided into 4 treatment groups
Group A: cervical cancer1 intervention
Group B: cervical intraepithelial neoplasm1 intervention
Group C: control1 intervention
Group D: ovarian cancer1 intervention

Trial outcomes

Primary outcomes

1

Vascularization-flow index

1. Compare the vascularization-flow index values between cervical cancer, cervical intraepithelial neoplasia and the control group. 2. To assess whether vascularization-flow index is a predictor of progression-free survival in women with ovarian cancer

Time frame
3 years

Secondary outcomes

1

Vascularization index

1\. Compare the vascularization index values between cervical cancer, cervical intraepithelial neoplasia and the control group. 2. To assess whether vascularization index is a predictor of progression-free survival in women with ovarian cancer

Time frame
3 years
2

Flow index

1\. Compare the flow index values between cervical cancer, cervical intraepithelial neoplasia and the control group. 2. To assess whether flow index is a predictor of progression-free survival in women with ovarian cancer

Time frame
3 years

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

This trial is not recruiting at the moment. You can still explore other options: