The Role of Chest Ultrasound in Patients With Respiratory Tract Infections

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeUp to 20
SponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS

About this trial

Respiratory tract infections are a major cause of hospitalization among pediatric and adult patients, regardless of the cause, whether viral or bacterial. It is critical to stratify each patient's risk to predict the subsequent clinical course. Point-of-care chest ultrasonography in parallel with clinical evaluation has been found to be an effective tool to assess the severity of pathology. A number of scores have been validated on the basis of the ultrasound picture. Currently, a growing interest is directed toward the unambiguous validation of an ultrasound score that can predict the patient's outcome in terms of hospitalization, ICU admission, need for a more pronounced approach in terms of respiratory care both qualitatively and quantitatively.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients aged 0 to 20 years with a clinical diagnosis of respiratory tract infection, evaluated in the emergency department and then discharged home or admitted to the Pediatric Intensive Care Unit or Pediatrics Department.

Informed consent signed by parents or patient of legal age

Disqualifiers

Refusal to sign informed consent

Patients with bronchopulmonary dysplasia

Foreign body aspiration cases

Patients with pulmonary malformations

Trial population

Patients aged 0 to 20 years with a clinical diagnosis of respiratory tract infection, evaluated in the emergency department and then discharged home or admitted to the Pediatric Intensive Care Unit or Pediatrics Department.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Ultrasound evaluation

    Diagnostic test

    The subjects will constitute a cohort whose medical history, clinical, ultrasound and treatment data reported in the appropriate data collection form will be prospectively collected. Enrolled patients will undergo clinical and ultrasonographic evaluation in a manner not unlike routine clinical practice.

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

The ultrasound pattern of patients with respiratory tract infections

To evaluate the ultrasound pattern of patients with respiratory tract infections by score.

Time frame
1 hour

Secondary outcomes

1

the duration of hospitalization

Validate a qualitative and quantitative ultrasound protocol to assess respiratory tract infections to predict the duration of hospitalization

Time frame
1 hour
2

Use the SatO2/FiO2 ratio to evaluate outcome

Use the SatO2/FiO2 ratio in conjunction with clinical assessment to evaluate the initiation of respiratory assistance with high-flow oxygen

Time frame
20 minutes
3

correlation between ultrasound score and vital parameters

Assess a correlation between ultrasound score and vital parameters (FR, HR, SatO2)

Time frame
1 hour
4

correlation between ultrasound score and indices of inflammation

Assess a correlation between ultrasound score and indices of inflammation (PCR, PCT)

Time frame
1 hour

Other outcomes

Sponsors and contacts

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This trial is not recruiting at the moment. You can still explore other options: