About this trial
Analyzing results of carotid graft interposition with and without flow preservation through external carotid artery after endarterectomy.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
symptomatic carotid stenosis (> 50%)
unilateral asymptomatic carotid stenosis (> 60%)
bilateral asymptomatic carotid stenosis (> 60%)
Disqualifiers
carotid restenosis
"major surgery" in previous 6 months
previous brain trauma or surgery
malignant disease
Trial population
Patients who underwent carotid artery surgery due to atherosclerotic symptomatic and asymptomatic disease had graft interposition conducted due to unsuccessful endarterectomy.
Trial design
Cohort
Retrospective
Treatments tested in this trial
Carotid graft interposition
Procedure/SurgeryIn patients with extensive atherosclerotic carotid disease, when endarterectomy isn't feasible, replacement of the carotid artery with a graft is needed. Graft interposition can be performed either by end-to-end proximal and distal anastomoses in the undiseased common and internal carotid artery with ligation of the external carotid artery, or by side-to-end proximal anastomosis on the origin of the internal carotid artery and end-to-end distal anastomosis on the internal carotid artery with flow preservation in the external carotid artery.
Treatment groups
Trial outcomes
Primary outcomes
periprocedural stroke and death
onset of new neurological deficit or death during perioperative period
myocardial infarction
development of new acute coronary events during perioperative period
stroke ipsilateral to the procedure
development of new neurological events that are pathophysiological atributable to the operated side
Secondary outcomes
restenosis rate
restenosis after graft placement diagnosed by color Doppler sonographic examination or by multiplanar detection computerized tomography angiography
graft patency
primary and primary assisted
patient survival
defining cause of death
Sponsors and contacts
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