The Role of POLE Mutation in High Risk Endometrial Cancer.
ConditionEndometrial Neoplasms
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
AgeNot listed
SponsorFar Eastern Memorial Hospital
About this trial
The actual role of POLE mutations in high-risk endometrial cancer is undetermined. The main question it aims to answer is:
What is the prevalence of POLE mutations in high-risk endometrial cancer case? What is the impact of POLE mutations in real world high-risk endometrial cancer case?
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
women with high-risk for recurrent endometrial cancer
Disqualifiers
Nil
Trial population
All high-risk endometrial cancer cases
Trial design
Design model
Cohort
Time perspective
Retrospective
Treatments tested in this trial
Not listed
Trial groups
150 Participants
are grouped into 1 trial groupGroup A: endometrial cancer
Trial outcomes
Primary outcomes
1
Prevalence of POLE mutation in high risk endometrial cancer
The prevalence of POLE mutations in women with high-risk for recurrent endometrial cancer
Time frame
2 yearsSecondary outcomes
1
The impact of POLE on overall survival
The impact of POLE on overall survival, compared with the other TCGA groups
Time frame
5 yearsSponsors and contacts
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Source ClinicalTrials.gov