The Role of Stress in Cardiac Arrest (Cortizol CPR)

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-100
SponsorUniversity Hospital Pilsen

About this trial

The aim of this study is to assess long-term stress in patients after an out-of-hospital cardiac arrest. To do this, we will measure levels of the stress hormone cortisol in hair samples. Cortisol is produced in larger amounts during periods of ongoing stress and builds up in the hair as it grows. Because hair grows about 1 cm per month, a 3 cm hair sample can show your average stress level over the past three months. The results will be compared with anonymized information from your medical records and the care you received before and during your hospital stay.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Cardiac arrest

Heart attack

18 - 100 years

Disqualifiers

Disapproval patient´s relatives with the study

Chronical treatment with corticoids and antidepresives

Trial design

Design model

Parallel

Treatments tested in this trial

  • Sample of hair

    Diagnostic test

    Sampling of 3cm of hair due to level of cortizol.

Treatment groups

136 Participants
are divided into 2 treatment groups
Group A: Cardiac arrestExperimental treatment 1 intervention
Group B: Heart attackExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Hair cortisol levels assessment in CA patients vs heart attack patients

Hair cortisol levels assessment in CA patients vs heart attack patients

Time frame
Enrollment

Secondary outcomes

1

Correlation of neurological outcomes using the CPC scale in CA patients with hair cortisol levels.

Correlation of neurological outcomes using the CPC scale in CA patients with hair cortisol levels.

Time frame
30 and 90 days after CA
2

Correlation between the severity of the post-resuscitation course according to the severity of organ damage (heart, lung, kidneys, brain ) and hair cortisol levels

Correlation between the severity of the post-resuscitation course according to the severity of organ damage (heart, lung, kidneys, brain ) and hair cortisol levels

Time frame
30 days after CA

Other outcomes

Sponsors and contacts

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