The Sensitivity and Specificity of Sniff Dog as a Tool in Diagnosing the Suspected Tumor Patients

ConditionNeoplasia

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age1+

SponsorChang-Qing Gao

About this trial

Previous studies have demonstrated that sniff dogs can identify cancer patients from healthy subjects through sniffing exhaled breath air or blood or serum or urine or feces. It is hypothesized that sniff dogs may be used as a tool in identifying cancer patients in the high risk population or suspected patients. Trained dogs will sniff serum from participants who are suspected to suffer from tumor by their physicians and not yet but will be diagnosed by pathological examination.The results will be compared with the outcome of the pathological examination.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Healthy volunteers who have been examined by the currently used procedures and find to be without tumors.

Patients in the breast surgery, thoracic surgery, gynecological and neurosurgery departments with lesions with characteristics of tumors

Disqualifiers

Patients who have had pathological results

Trial population

* Healthy volunteers who have been examined by the currently used procedures and find to be without tumors. * Patients in the breast surgery, thoracic surgery, gynecological and neurosurgery departments with lesions with characteristics of tumors

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

2,000 Participants

are grouped into 5 trial groups

Group A: Healthy volunteers

Group B: Suspected breast cancer subjects

Group C: Suspected lung cancer subjects

Group D: Suspected neurological tumor subjects

Group E: Suspected patients with gynecological tumor

Trial outcomes

Primary outcomes

sensitivity and specificity of the sniff dogs as a tool in diagnosing tumors

The results that obtained from the dogs will be compared with these of the pathological examinations. Sensitivity = the No. of patients identified by the dogs as cancers / the No. of patients suffering from cancer confirmed by pathological examination. Specificity = No. of subjects signaled by the dog as non-cancers / No. of subjects confirmed by pathological examination as non-cancer subjects.

Time frame

12 months

Secondary outcomes

behavior patterns of the sniff dogs to different diseases

The behavior (lying before the tank for positive, neglecting the tanks) of the dog will be recorded and compared with the results of the pathological examination.

Time frame

12 months

Other outcomes

the substances used for identifying tumors by the sniff dogs

GCMS etc will be used to compare the volatile compounds between the sera from cancers patients and the from non-cancer subjects, the suspected VOCs will be tested by the dog for conformation.

Time frame

12 months

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Chang-Qing Gao

Lead sponsor

Central South University

Sponsor institution

Source ClinicalTrials.gov

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