About this trial
we study the circulating T-follicular regulatory and T-follicular regulatory cells in autoimmune hemolytic anemia.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Patients diagnosed as autoimmune hemolytic anemia, primary or secondary, male or female, any age but not on treatment
Disqualifiers
Pregnancy or breast-feeding women
Patients treated with corticoids or immunosuppressant.
Patients with hematological malignance.
Patients with alloimmune hemolytic anemia as ABO incompatibility or transplant patients
Trial population
The sample size is 50 (25 in each arm) but number of controls will be decreased and number of cases will be increased
Trial design
Case-control
Retrospective
Treatments tested in this trial
flowcytometry
Diagnostic testThe study of CD4,CD25,FOXP3 and PD-1 on peripheral blood sample
Treatment groups
Trial outcomes
Primary outcomes
The proportion of circulating T-follicular helper and T-follicular regulatory in patients with Autoimmune Hemolytic Anemia (AIHA), at diagnosis and after treatment
Secondary outcomes
Measure the ratio between the T- follicular helper and T-follicular regulatory
Locations
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options: