About this trial
The goal of this observational study is to learn about the relationship between sleep alterations following anesthesia and their relationship to a potential increase of obstructive sleep apnea (OSA) severity.
Our main question is: Is there an increased severity of OSA on the third post-operative night compared to the first post-operative night and does this have a relation with REM sleep?
Participants enrolled in this research are all diagnosed with OSA, with or without treament. All participants will be asked to wear a watchlike device called WATCHPAT to identify sleep paterns and register apneic (no breathing) and hypopneic (insufficient breathing) incidents. We ask our participants to wear this device for 8-10 hours a night when they are a sleep.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients scheduled for elective surgery at the operating theatres of the AUMC with a diagnosis of OSA with or without treatment with an expected admittance of a minimum of 3 days
Patients with continuous positive airway pressure (CPAP) or mandibular advancement device (MAD) are considered patients with treatment for OSA
Patients ≥ 18 years
Dutch or English speaking
Disqualifiers
Patients < 18 years
Not speaking Dutch or English
Patients who do not sign consent for re-use of care data
Surgery scheduled in day case or with an expected discharge before the third night after surgery
Trial population
Patients scheduled for elective surgery at the operating theatres of the AUMC with a diagnosis of OSA with or without treatment with an expected admittance of a minimum of 3 days
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
AHI and Desaturations on night one and three after surgery
To compare the AHI and desaturations on night one and night three after surgery
Secondary outcomes
Desaturations post operatively
Assess the amount of patients with na increase of respiratory events (saturation \<90%) later than 6 hours after surgery.
AHI directly post-operatively
compare the difference between AHI and desaturations in the first six hours after surgery to the first night after surgery.
Changes in total REM sleep
Changes in total REM sleep comparing night 1,2 and 3.
Changes in AHI, REM-AHI and desaturations over time
To analyze the changes over time in AHI, REM-AHI, (respiratory events related tot REM-sleep cycle) and desaturations.
Sponsors and contacts
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Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Lead sponsor
VU University of Amsterdam
Collaborator