The Social Regulation of Threat-related Vigilance and Arousal

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorUniversity of Nevada, Reno

About this trial

This study will examine the effects of social support on threat vigilance and arousal using eye tracking. We will also test the moderating effects of trauma and discrimination history.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

In a stable romantic relationship for 6 months or more

Normal vision or corrected-to-normal vision

Fluent in English

Disqualifiers

If vision is corrected-to-normal, needs to use hard contact lenses, bifocal contact lenses, or glasses

Experienced a traumatic event within the past 4 weeks

Trial design

Design model

Crossover

Treatments tested in this trial

  • social support

    Behavioral

    social support is provided in the form of social touch (hand holding)

Treatment groups

45 Participants
are divided into 3 treatment groups
Group A: Social support from a romantic partnerExperimental treatment 1 intervention
Group B: Social support from a strangerActive comparator 1 intervention
Group C: No social supportNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Vigilance Related Eye Movements - Number of Eye Fixations

Participants will view 15 pictures of natural environmental scenes for 10 seconds per image. We will use an eye tracker to examine the number of eye fixations per scene. A greater number of fixations during the 10 second presentation of a scene would indicate greater vigilance.

Time frame
Collected from minute 15 to minute 45 of study participation, approximately
2

Vigilance Related Eye Movements - Visual Scanning

Participants will view 15 pictures of natural environmental scenes for 10 seconds per image. We will use an eye tracker to examine the proportion of the scene that they look at (fixate on) out of approximately 80 possible sectors. A greater proportion of the scene they fixate on would indicate greater vigilance.

Time frame
Collected from minute 15 to minute 45 of study participation, approximately
3

Threat-Related Physiological Arousal - Pupil Dilation

Participants will view a series of visual cues (either an 'X' or an 'O') where an 'X' signals a possible (20% probability) aversive auditory stimulus (human scream). We will examine pupil dilation during the task in order to measure arousal in response to uncertain threat. We will calculate average pupil dilation during the wait period after threat cues (X) and after safety cues (O). We will subtract average pupil dilation after safety cues from threat cues to create an index of threat-related arousal. Greater pupil dilation (for threat minus safety cues) would indicate greater threat-related arousal.

Time frame
Collected from minute 45 to minute 75 of study participation, approximately

Secondary outcomes

Other outcomes

Sponsors and contacts

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