About this trial
Orthotopic sigmoid neobladder surgery is one of the ideal urinary diversion methods after radical cystectomy.In recent years, functional imaging studies have revealed brain regions related to urinary system function, but brain activity of lower urinary tract function in neobladder patients is still unclear.The aim of this study is to explore the brain activity of urination intention and self-controlled urination behavior in patients with orthotopic sigmoid neobladder by task-state functional magnetic resonance imaging (fMRI).
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Being right-handed;
3 months or more after operation;
No contraindications to fMIR examination;
Voluntarily sign informed consent.
Disqualifiers
History of bladder radiotherapy;
History of prostate cancer;
Suffering from diseases affecting abdominal pressure;
History of abnormal brain anatomy, craniocerebral surgery, craniocerebral tumor, and craniocerebral radiotherapy;
Trial population
Patients 3 months or more after orthotopic neobladder surgery.
Trial design
Cohort
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
The location of brain functional activation areas
Areas of the brain where excitation or inhibition occurs in fMRI images
The peak T-value size of the activation region
Peak T values of activated or inhibited regions of the brain in fMRI images
Sponsors and contacts
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