This study evaluates a new single-beat echocardiographic technique (TE-e', the time difference between the onset of the mitral inflow E wave and the septal e' wave on tissue Doppler imaging) for estimating left atrial pressure (LAP) in critically ill patients, comparing it against the standard two-beat method. The goal is to determine whether the faster, single-beat method gives results as reliable as the conventional method, and whether it can help identify patients with elevated left atrial pressure without an invasive procedure.
Adult patients ≥18 years admitted to the QMH Adult Intensive Care Unit (AICU)
Requiring a transthoracic echocardiogram (TTE) as part of routine clinical care
TE-e' obtainable by both the conventional and the novel method
Patients <18 years of age
Patients in atrial fibrillation
Patients with a poor TTE acoustic window
Patients in whom TE-e' is technically difficult to obtain or interpret by either method
Patients admitted to Adult Intensive Care Unit requiring a TTE
Cohort
Prospective
Echocardiography
Diagnostic testFull echocardiogram performed on recruited patients.
Correlation between novel (single-beat) and conventional (two-beat) TE-e' values
Correlation between novel and conventional methods in obtaining septal e' and s' velocities - At time of index TTE
Correlation between clinical evaluation of LAP and TE-e' value
Correlation between other echocardiographic parameters of LAP (E/A ratio, LAVi, TR Vmax, lung ultrasound 6-point protocol) and TE-e' value
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