About this trial
Objectives/Hypotheses
1. Prehospital termination-of-resuscitation (TOR) rules were developed in North American and European sites. Whether they remained valid in different geographic, ethnic, and cultural background areas is still under debate. 2. Differences in characteristics of out-of-hospital cardiac arrests (OHCAs) and configurations of emergency medical service (EMS) between the Western and Asian countries, including relatively lower rate of presenting shockable rhythm (i.e. ventricular fibrillation / ventricular tachycardia; VF/VT), lower rates of bystander CPR, less advanced life support (ALS) implementation, and less public access defibrillators, might create potential threats to the prediction accuracy of TOR rules. 3. We aim to conduct a study to validate the performance of ever published TOR rules in Asian OHCA population, including non-traumatic, traumatic, and pediatric OHCA patients. Furthermore, assess the possible variables that may impact the performance of TOR rules. 4. We also aim to develop new TOR rules based on PAROS registry for Asia population, focusing on non-traumatic, traumatic, and pediatric OHCA patients, respectively.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
out of hospital cardiac arrest (OHCA) patients
Disqualifiers
age <18 years
non-EMS transport to the emergency department
obvious signs of death (e.g. decapitation, rigor mortis, lividity, and decapitation) or having do-not-resuscitate (DNR) orders
missing data despite meeting the inclusion criteria.
Trial population
The study population included adults, OHCA patients since1 January 2007, identified from the PAROS registry. The PAROS data encompass 13 countries. The exclusion criteria include: (1) age \<18 years, (2) non-EMS transport to the emergency department, (3) obvious signs of death (e.g. decapitation, rigor mortis, lividity, and decapitation) or having do-not-resuscitate (DNR) orders, and (4) missing data despite meeting the inclusion criteria.
Trial design
Other
Other
Treatments tested in this trial
termination of resuscitation rules
Other interventionUse retrospective data to analyze the accuracy termination of resuscitation rules and further develope a termination of resuscitation rule.
Treatment groups
Trial outcomes
Primary outcomes
survival to hospital discharge
survival to 30-day hospitalisation
Secondary outcomes
Cerebral Performance Categories Scale (CPC)
CPC Scale 1\~5, minimum value: 1; maximum value:5; lower score means greater outcome
Sponsors and contacts
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National Taiwan University Hospital
Lead sponsor
Singapore Clinical Research Institute
Collaborator