The Value of a Convolutional Neural Network-Based Renal Artery Perfusion Model in Predicting Renal Function After Partial Nephrectomy: A Prospective Study

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorShao Pengfei

About this trial

The goal of this observational study is to develop a CNN-based machine module to predict postoperative fractional renal function in people who are proposed to undergo partial nephrectomy. The main question it aims to answer is:

• Does this machine learning model accurately predict renal function after partial nephrectomy?

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

people with stage cT1 renal tumors confirmed by preoperative CT or MR

people who are proposed to undergoing partial nephrectomy

localized renal tumors without lymph node and distant metastases as defined by NCCN guidelines

ECOG score of 0 or 1

Disqualifiers

people with surgically unresectable lesions

people with Abnormal preoperative renal function, eGFR(estimated by CKD-EPI)<90ml/min/1.73m2

people who receive preoperative molecular targeted therapy, immunotherapy, chemotherapy

people with any contraindications to surgery

Trial population

people with localized renal tumors scheduled for partial nephrectomy

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

GFR of ipsilateral and contralateral kidneys

Time frame
3 months after surgery
2

volume of ipsilateral kidney

Time frame
3 months after surgery

Secondary outcomes

1

Postoperative total renal function(eGFR)

Time frame
24 hours, 1 month, 3 months, 6 months, 1 year after surgery

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Shao Pengfei

Lead sponsor

The First Affiliated Hospital with Nanjing Medical University

Sponsor institution