The Value of Advanced Imaging Sequences for Fetal MRI in Clinical Practice

ConditionFetal Conditions

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexFemale

AgeNot listed

SponsorSheffield Teaching Hospitals NHS Foundation Trust

About this trial

This project is split into 4 sections:

1. Can improvements be made in the Magnetic resonance imaging sequences used to image the fetus in order to improve diagnostic accuracy? 2. Does 3T improve the quality and diagnostic value of fetal MRI when compared to 1.5T 3. Can fetal MRI be used to image the fetal heart? 4. Can fetal MRI be used to image the fetal Bones?

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Pregnant women who are attending the fetal medicine clinic and are asked to consider an MRI scan to provide information to help manage the current pregnancy.

Pregnant women requesting a termination of pregnancy who will allow us to do fetal MRI at 3T prior to the termination.

Disqualifiers

Contraindication to MRI

Severe claustrophobia

Trial design

Design model

Parallel

Treatments tested in this trial

MRI scan
Diagnostic test
Addition of advanced imaging sequences for fetal MRI

Treatment groups

150 Participants

are divided into 4 treatment groups

Group A: Patients attending for a clinical scanOther 1 intervention

Group B: Patients who have requested a TOPOther 1 intervention

Group C: Patients with fetal heart abnormalityOther 1 intervention

Group D: Patient fetal bone abnormalitiesOther 1 intervention

Trial outcomes

Primary outcomes

Establish the value of advanced imaging sequences for fetal MRI in clinical practice

Part 1: improved imaging sequences that show areas better than the original sequences. Part 2: improved image quality when compared to similar (historical)cases done at 1.5T. Part 3 and 4: imaging of the fetal heart and bone that will be useful clinically (currently the images are not good enough to provide information for diagnosis and management) Overall improved image detail and quality to aid diagnosis and management.

Time frame

3 years

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Sheffield Teaching Hospitals NHS Foundation Trust

Lead sponsor

University of Sheffield

Collaborator

Source ClinicalTrials.gov

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