The Variation in Electrode Configuration for Termination of Out-of-Hospital Rhythms That Are Shockable in Cardiac Arrest Trial

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorOregon Health and Science University

About this trial

The purpose of this study is to compare the effectiveness of two defibrillator pad placements, one where pads are placed on the front of the chest and back (anterior-posterior \[AP\]) and one where the pads are placed on the front and side of the chest (anterior-lateral \[AL\]), for the treatment of cardiac arrest. Both pad placement locations are recommended for use by the American Heart Association (AHA) and International Liaison Committee on Resuscitation (ILCOR) and are used in standard treatment. The investigators are hoping to find out if one pad position is more effective than the other in the treatment of cardiac arrest.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Emergency medical services (EMS)-treated non-traumatic out-of-hospital cardiac arrest

Disqualifiers

ROSC at EMS arrival (e.g., bystander AED shock with ROSC prior to EMS care) without rearrest during EMS care

Known prisoners

Known pregnant patients

Known pediatric patients (treated under the pediatric algorithm, generally <15 years)

Trial design

Design model

Crossover

Treatments tested in this trial

  • defibrillator electrode pads

    Device

    Application of defibrillator electrode pads to be used in cardiac arrest treatment

Treatment groups

1,500 Participants
are divided into 2 treatment groups
Group A: Anterior-PosteriorActive comparator 1 intervention
Group B: Anterior-LateralActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Post-Shock Return of Spontaneous Circulation (ROSC)

Any palpable pulse documented at any time after the first EMS shock

Time frame
day 1

Secondary outcomes

1

Time to first rhythm analysis

Time from EMS arrival on-scene for non-EMS witnessed arrests and first rhythm analysis by the defibrillator

Time frame
day 1
2

Time to initial shock

Time from EMS arrival on-scene for non-EMS witnessed arrests and initial shock by EMS

Time frame
day 1
3

Total EMS shocks

Total shocks given by EMS

Time frame
day 1
4

Time to ROSC

Time to ROSC from initial shock with competing risks (e.g. termination of resuscitation, pad change, double sequential external defibrillation use)

Time frame
day 1

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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