The Venous Distension Reflex and Orthostatic Hypertension

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMilton S. Hershey Medical Center

About this trial

This research is being done to find out whether distension of veins in legs will cause a rise in blood pressure (orthostatic hypertension).

Eligibility criteria

Qualifiers

Are capable of giving informed consent

Are of any race or ethnicity

Are fluent in written and spoken English

Whose history and physical exam did not uncover any

Disqualifiers

Are 18 years of age

Systolic BP (SBP) during standing is at least 10 mmHg > the supine SBP

Patients with a diagnosis of stage I hypertension without other chronic diseases may be INCLUDED

The change in SBP by standing is within ± 5 mmHg from the supine SBP

Trial design

Treatments tested in this trial

  • Tilt + external pressure
  • Tilt + no external pressure.
  • Limb occlusion + negative pressure
  • Limb occlusion + no negative pressure

Treatment groups

30 Participants
are divided into 4 treatment groups