Therapeutic Evaluative Conditioning to Reduce Adolescents' Self-injurious Thoughts and Behaviors During and After Psychiatric Inpatient Hospitalization

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age12-19
SponsorFranciscan Hospital For Children, INC.

About this trial

Suicide is the 2nd leading cause of death among adolescents, with the highest risk period for suicide being the month following psychiatric inpatient hospitalization. The investigators propose testing a brief, scalable intervention using evaluative conditioning aimed at reducing suicidal thoughts and behaviors among adolescents during and after inpatient hospitalization. Scalable interventions, such as the one proposed that reduce suicide risk during this markedly high-risk period, could result in large-scale decreases in suicide death.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Be a patient on McLean-Franciscan Child and Adolescent Inpatient Program (MF-CAIP) of Franciscan Children's (FC)

Be 12-19 years-old

Own a smartphone

Have a parent/guardian that can provide permission

Disqualifiers

Any factor that impairs an individual's ability to comprehend and effectively participate in the study, including

an inability to speak or write English fluently

the presence of gross cognitive impairment due to florid psychosis, intellectual disability, dementia, acute intoxication, etc., or the presence of extremely agitated or violent behavior

a potential discharge location anticipated to be a residential program in which the average length of stay is more than 14 days

Trial design

Design model

Parallel

Treatments tested in this trial

  • Therapeutic Evaluative Conditioning

    Behavioral

    Participants are told which pictures are "matched pairs." They find the "matched pairs" among 4 or 8 pictures. By associating pictures and words associated with SITB (e.g., pictures of cut skin, pictures of people engaging in potentially suicidal behaviors, and the word "death") with naturally aversive images (e.g., snakes and spiders), it increases the aversion to SITB. The second goal is to increase liking toward the self by pairing self-relevant stimuli (e.g., the participant's name or other self-relevant details, as well as words like "I" and "me").

  • Neutral comparison condition

    Behavioral

    Match neutral pictures to account for doing an intervention.

Treatment groups

155 Participants
are divided into 2 treatment groups
Group A: Active intervention armActive comparator 1 intervention
Group B: Control armSham comparator 1 intervention

Trial outcomes

Primary outcomes

1

Self-injurious thoughts and behaviors

The investigators will assess the presence and frequency of non-suicidal self-injury, suicidal thoughts, suicide plans, suicide attempts and other suicidal behaviors, such as aborted suicide attempts. The investigators will also assess the severity of suicidal thoughts as well.

Time frame
During inpatient hospitalization (average 14 days), plus an additional two months post- hospitalization.

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Franciscan Hospital For Children, INC.

Lead sponsor

National Institute of Mental Health (NIMH)

Collaborator

Harvard University

Collaborator