Health TrialsbyHealthPanel

Therapeutic Wavelength Nanotechnology Devices in Alveolar Preservation

ConditionsTooth AvulsionTooth Crown Fracture
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-80
SponsorUniversity of Bari Aldo Moro

About this trial

After tooth extraction, a progressive alveolar bone resorption is observed. Alveolar ridge preservation consists of placing a biomaterial within the extraction socket and covering it with a membrane.

This procedure helps limit physiological bone resorption, making the soft and hard tissue profile of the edentulous site more prosthetically favorable.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Adults in good general health

Indication for tooth extraction in sites planned for delayed implant placement

Inability to place immediate post-extraction implants due to insufficient residual bone to ensure primary stability

Extraction sockets presenting absence of the buccal (vestibular) bone wall

Disqualifiers

Systemic conditions affecting bone healing

Uncontrolled periodontal disease

Smoking >10 cigarettes/day

Pregnancy or lactation

Trial design

Design model

Parallel

Treatments tested in this trial

  • Socket Preservation

    Procedure/Surgery

    After atraumatic tooth extraction, the socket is filled with a xenogeneic bone graft enriched with hyaluronic acid, which enhances biological activity by promoting angiogenesis, cell migration, and early wound healing. The grafted site is then covered with a dermal matrix membrane, providing mechanical protection, stabilization of the biomaterial, and guided tissue regeneration.

Treatment groups

20 Participants
are divided into 2 treatment groups
Group A: Traditional Alveolar PreservationActive comparator 1 intervention
Group B: therapeutic wavelengths Alveolar PreservationExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

VAS

Postoperative pain assessment using the Visual Analog Scale (VAS) (1-10)

Time frame
1 day , 3 days , 7 days ,14 days
2

Analgesic consumption

recorded as the number of ibuprofen 400 mg tablets taken

Time frame
7 days

Secondary outcomes

1

Histological Evaluation

* Prior to implant placement, a CBCT scan will be performed to assess alveolar bone volume and morphology. * During implant site preparation, a bone core biopsy will be harvested using a trephine bur. * The bone sample will undergo histological and histomorphometric analysis to evaluate: * New bone formation * Residual graft material * Connective tissue percentage

Time frame
4- 6 month

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Bari Aldo Moro

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: